Randomized trials of antihypertensive therapy are endpoints (for example, left ventricular hyperrelatively short in duration (3 to 5 years) and, when trophy or atherosclerotic plaque development). In based on monitoring of the mortal and morbid the future, more and more antihypertensive drugs events occurring during this period of time, repre- will be tested to assess their ability to interfere sent short-term perspectives of antihypertensive with both cardiovascular disease and cardiovascu- therapy. In cases of mild-to-moderate hypertension, lar events. Am J Hypertens 1993;6:2S-5S however, the goal of antihypertensive therapy is not the prevention of impending events but, rather, the avoidance or retardation of cardiovascular le- key words: Antihypertensive therapy, cardiovas- sions. These long-term perspectives can only be ex- cular events, cardiovascular disease, left ventricular plored by randomized trials that monitor surrogate hypertrophy, atherosclerotic plaque.
ASJC Scopus subject areas
- Internal Medicine
- Cardiology and Cardiovascular Medicine