Abstract
Objective: To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings. Methods: Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage-of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the E autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min EGG. Results: All of the time domain measurements had an ICC ≤ 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration. Conclusion: The reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation.
| Original language | English |
|---|---|
| Pages (from-to) | 226-233 |
| Number of pages | 8 |
| Journal | Cardiovascular Research |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Aug 1996 |
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Keywords
- Heart rate variability
- Human
- Spectral analysis
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Short- and long-term reproducibility of time and frequency domain heart rate variability measurements in normal subjects. / Pitzalis, Maria Vittoria; Mastropasqua, Filippo; Massari, Francesco; Forleo, Cinzia; Di Maggio, Marinella; Passantino, Andrea; Colombo, Roberto; Di Biase, Matteo; Rizzon, Paolo.
In: Cardiovascular Research, Vol. 32, No. 2, 08.1996, p. 226-233.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Short- and long-term reproducibility of time and frequency domain heart rate variability measurements in normal subjects
AU - Pitzalis, Maria Vittoria
AU - Mastropasqua, Filippo
AU - Massari, Francesco
AU - Forleo, Cinzia
AU - Di Maggio, Marinella
AU - Passantino, Andrea
AU - Colombo, Roberto
AU - Di Biase, Matteo
AU - Rizzon, Paolo
PY - 1996/8
Y1 - 1996/8
N2 - Objective: To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings. Methods: Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage-of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the E autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min EGG. Results: All of the time domain measurements had an ICC ≤ 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration. Conclusion: The reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation.
AB - Objective: To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings. Methods: Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage-of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the E autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min EGG. Results: All of the time domain measurements had an ICC ≤ 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration. Conclusion: The reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation.
KW - Heart rate variability
KW - Human
KW - Spectral analysis
UR - http://www.scopus.com/inward/record.url?scp=0030222178&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030222178&partnerID=8YFLogxK
U2 - 10.1016/0008-6363(96)00086-7
DO - 10.1016/0008-6363(96)00086-7
M3 - Article
VL - 32
SP - 226
EP - 233
JO - Cardiovascular Research
JF - Cardiovascular Research
SN - 0008-6363
IS - 2
ER -