Abstract
Short sleep duration has a substantial influence on the overall health of an individual. Short sleep time can be a consequence of lifestyle habits, environmental factors, or the presence of a sleep disorder, such as insomnia or sleep-disordered breathing. Short sleep time is associated with increased morbidity and mortality, mainly from cardiovascular disorders (including coronary artery disease, arrhythmias, and hypertension). Several biological mechanisms have been proposed as a possible link between short sleep duration and these diseases, such as involvement of the autonomic nervous system, endothelial function, metabolic regulation, inflammation, and the coagulation system. In this Review, we provide an overview on the effects of short sleep duration on cardiovascular health and diseases and discuss the main pathophysiological mechanisms involved, taking into account both experimental data and clinical evidence.
| Original language | English |
|---|---|
| Pages (from-to) | 213-224 |
| Journal | Nature Reviews Cardiology |
| Volume | 16 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2019 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Short sleep duration and cardiometabolic risk : from pathophysiology to clinical evidence. / Tobaldini, Eleonora; Fiorelli, Elisa M.; Solbiati, Monica; Costantino, Giorgio; Nobili, Lino; Montano, Nicola.
In: Nature Reviews Cardiology, Vol. 16, No. 4, 2019, p. 213-224.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Short sleep duration and cardiometabolic risk
T2 - from pathophysiology to clinical evidence
AU - Tobaldini, Eleonora
AU - Fiorelli, Elisa M.
AU - Solbiati, Monica
AU - Costantino, Giorgio
AU - Nobili, Lino
AU - Montano, Nicola
PY - 2019
Y1 - 2019
N2 - Short sleep duration has a substantial influence on the overall health of an individual. Short sleep time can be a consequence of lifestyle habits, environmental factors, or the presence of a sleep disorder, such as insomnia or sleep-disordered breathing. Short sleep time is associated with increased morbidity and mortality, mainly from cardiovascular disorders (including coronary artery disease, arrhythmias, and hypertension). Several biological mechanisms have been proposed as a possible link between short sleep duration and these diseases, such as involvement of the autonomic nervous system, endothelial function, metabolic regulation, inflammation, and the coagulation system. In this Review, we provide an overview on the effects of short sleep duration on cardiovascular health and diseases and discuss the main pathophysiological mechanisms involved, taking into account both experimental data and clinical evidence.
AB - Short sleep duration has a substantial influence on the overall health of an individual. Short sleep time can be a consequence of lifestyle habits, environmental factors, or the presence of a sleep disorder, such as insomnia or sleep-disordered breathing. Short sleep time is associated with increased morbidity and mortality, mainly from cardiovascular disorders (including coronary artery disease, arrhythmias, and hypertension). Several biological mechanisms have been proposed as a possible link between short sleep duration and these diseases, such as involvement of the autonomic nervous system, endothelial function, metabolic regulation, inflammation, and the coagulation system. In this Review, we provide an overview on the effects of short sleep duration on cardiovascular health and diseases and discuss the main pathophysiological mechanisms involved, taking into account both experimental data and clinical evidence.
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UR - http://www.scopus.com/inward/citedby.url?scp=85056150591&partnerID=8YFLogxK
U2 - 10.1038/s41569-018-0109-6
DO - 10.1038/s41569-018-0109-6
M3 - Article
AN - SCOPUS:85056150591
VL - 16
SP - 213
EP - 224
JO - Nature Reviews Cardiology
JF - Nature Reviews Cardiology
SN - 1759-5002
IS - 4
ER -