Short-term effects of a hypocaloric diet and a physical activity programme on weight loss and exercise capacity in obese subjects with chronic ischaemic heart disease: A study in everyday practice

Luca Alessandro Gondoni, Anna Maria Titon, Ferruccio Nibbio, Giulia Caetani, Giovanni Augello, Ornella Mian, Cristina Tuzzi, Eva Averna, Cinzia Parisio, Antonio Liuzzi

Research output: Contribution to journalArticle

Abstract

Objective - The objective of this paper is to describe the effects of a rehabilitation programme in obese patients affected with chronic ischaemic heart disease; to identify the factors that influence weight loss and improvement in exercise capacity in everyday practice. Methods and results - We studied 562 white patients (381 men) who followed a 23.3 ± 3.9 days in-hospital programme. They attended daily sessions of aerobic activity (cycloergometer, walking, and strength exercise); a low-calorie diet was set at approximately 80% of resting energy expenditure. By the end of the programme BMI decreased from 38.0 ± 4.9 to 36.7 ± 4.8 kg/m2 (P <0.001). Attained metabolic equivalents (METs) increased from 6.2 ± 2.5 METs to 7.3 ± 2.7 (P <0.001). Age, sex, presence of diabetes and education level were significantly related to the outcomes. Patients who took beta-blockers and statins had less BMI improvement: -1.2 ± 0.7 kg/m2 vs.-1.4 ± 0.6 (P = 0.013) and -1.3 ± 0.6 vs. -1.4 ± 0.7 (P = 0.023), respectively. Patients that took diuretics and angiotensin receptor blockers (ARB) had less improvement in exercise capacity: 0.9 ± 1.0 METS vs. 1.3 ± 1.3 (P <0.001) and 0.8 ± 1.3 vs. 1.2 ± 1.3 (P = 0.011), respectively. After a median interval of 358 days, 152 patients were seen at a follow-up visit: their BMI increased by 1.0 ± 2.4 kg/m 2 and only 21% of patients lost weight. Conclusions - Rehabilitation improves exercise capacity and induces significant weight loss in obese patients with stable IHD, but women, diabetic, elderly and poorly educated subjects obtained unsatisfactory results. Use of diuretics and ARB seem to worsen the results. At follow-up only a small percentage of patients further improves BMI.

Original languageEnglish
Pages (from-to)153-159
Number of pages7
JournalActa Cardiologica
Volume63
Issue number2
DOIs
Publication statusPublished - Apr 2008

Fingerprint

Weight Reduction Programs
Myocardial Ischemia
Exercise
Diet
Metabolic Equivalent
Angiotensin Receptor Antagonists
Diuretics
Weight Loss
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Exercise Therapy
Caloric Restriction
Energy Metabolism
Walking
Rehabilitation
Education
Weights and Measures

Keywords

  • Exercise tolerance
  • Ischaemic heart disease
  • Obesity
  • Weight loss

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Short-term effects of a hypocaloric diet and a physical activity programme on weight loss and exercise capacity in obese subjects with chronic ischaemic heart disease : A study in everyday practice. / Gondoni, Luca Alessandro; Titon, Anna Maria; Nibbio, Ferruccio; Caetani, Giulia; Augello, Giovanni; Mian, Ornella; Tuzzi, Cristina; Averna, Eva; Parisio, Cinzia; Liuzzi, Antonio.

In: Acta Cardiologica, Vol. 63, No. 2, 04.2008, p. 153-159.

Research output: Contribution to journalArticle

Gondoni, Luca Alessandro ; Titon, Anna Maria ; Nibbio, Ferruccio ; Caetani, Giulia ; Augello, Giovanni ; Mian, Ornella ; Tuzzi, Cristina ; Averna, Eva ; Parisio, Cinzia ; Liuzzi, Antonio. / Short-term effects of a hypocaloric diet and a physical activity programme on weight loss and exercise capacity in obese subjects with chronic ischaemic heart disease : A study in everyday practice. In: Acta Cardiologica. 2008 ; Vol. 63, No. 2. pp. 153-159.
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abstract = "Objective - The objective of this paper is to describe the effects of a rehabilitation programme in obese patients affected with chronic ischaemic heart disease; to identify the factors that influence weight loss and improvement in exercise capacity in everyday practice. Methods and results - We studied 562 white patients (381 men) who followed a 23.3 ± 3.9 days in-hospital programme. They attended daily sessions of aerobic activity (cycloergometer, walking, and strength exercise); a low-calorie diet was set at approximately 80{\%} of resting energy expenditure. By the end of the programme BMI decreased from 38.0 ± 4.9 to 36.7 ± 4.8 kg/m2 (P <0.001). Attained metabolic equivalents (METs) increased from 6.2 ± 2.5 METs to 7.3 ± 2.7 (P <0.001). Age, sex, presence of diabetes and education level were significantly related to the outcomes. Patients who took beta-blockers and statins had less BMI improvement: -1.2 ± 0.7 kg/m2 vs.-1.4 ± 0.6 (P = 0.013) and -1.3 ± 0.6 vs. -1.4 ± 0.7 (P = 0.023), respectively. Patients that took diuretics and angiotensin receptor blockers (ARB) had less improvement in exercise capacity: 0.9 ± 1.0 METS vs. 1.3 ± 1.3 (P <0.001) and 0.8 ± 1.3 vs. 1.2 ± 1.3 (P = 0.011), respectively. After a median interval of 358 days, 152 patients were seen at a follow-up visit: their BMI increased by 1.0 ± 2.4 kg/m 2 and only 21{\%} of patients lost weight. Conclusions - Rehabilitation improves exercise capacity and induces significant weight loss in obese patients with stable IHD, but women, diabetic, elderly and poorly educated subjects obtained unsatisfactory results. Use of diuretics and ARB seem to worsen the results. At follow-up only a small percentage of patients further improves BMI.",
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AU - Titon, Anna Maria

AU - Nibbio, Ferruccio

AU - Caetani, Giulia

AU - Augello, Giovanni

AU - Mian, Ornella

AU - Tuzzi, Cristina

AU - Averna, Eva

AU - Parisio, Cinzia

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