Abstract
Objective - The objective of this paper is to describe the effects of a rehabilitation programme in obese patients affected with chronic ischaemic heart disease; to identify the factors that influence weight loss and improvement in exercise capacity in everyday practice. Methods and results - We studied 562 white patients (381 men) who followed a 23.3 ± 3.9 days in-hospital programme. They attended daily sessions of aerobic activity (cycloergometer, walking, and strength exercise); a low-calorie diet was set at approximately 80% of resting energy expenditure. By the end of the programme BMI decreased from 38.0 ± 4.9 to 36.7 ± 4.8 kg/m2 (P <0.001). Attained metabolic equivalents (METs) increased from 6.2 ± 2.5 METs to 7.3 ± 2.7 (P <0.001). Age, sex, presence of diabetes and education level were significantly related to the outcomes. Patients who took beta-blockers and statins had less BMI improvement: -1.2 ± 0.7 kg/m2 vs.-1.4 ± 0.6 (P = 0.013) and -1.3 ± 0.6 vs. -1.4 ± 0.7 (P = 0.023), respectively. Patients that took diuretics and angiotensin receptor blockers (ARB) had less improvement in exercise capacity: 0.9 ± 1.0 METS vs. 1.3 ± 1.3 (P <0.001) and 0.8 ± 1.3 vs. 1.2 ± 1.3 (P = 0.011), respectively. After a median interval of 358 days, 152 patients were seen at a follow-up visit: their BMI increased by 1.0 ± 2.4 kg/m 2 and only 21% of patients lost weight. Conclusions - Rehabilitation improves exercise capacity and induces significant weight loss in obese patients with stable IHD, but women, diabetic, elderly and poorly educated subjects obtained unsatisfactory results. Use of diuretics and ARB seem to worsen the results. At follow-up only a small percentage of patients further improves BMI.
| Original language | English |
|---|---|
| Pages (from-to) | 153-159 |
| Number of pages | 7 |
| Journal | Acta Cardiologica |
| Volume | 63 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 2008 |
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Keywords
- Exercise tolerance
- Ischaemic heart disease
- Obesity
- Weight loss
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Short-term effects of a hypocaloric diet and a physical activity programme on weight loss and exercise capacity in obese subjects with chronic ischaemic heart disease : A study in everyday practice. / Gondoni, Luca Alessandro; Titon, Anna Maria; Nibbio, Ferruccio; Caetani, Giulia; Augello, Giovanni; Mian, Ornella; Tuzzi, Cristina; Averna, Eva; Parisio, Cinzia; Liuzzi, Antonio.
In: Acta Cardiologica, Vol. 63, No. 2, 04.2008, p. 153-159.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Short-term effects of a hypocaloric diet and a physical activity programme on weight loss and exercise capacity in obese subjects with chronic ischaemic heart disease
T2 - A study in everyday practice
AU - Gondoni, Luca Alessandro
AU - Titon, Anna Maria
AU - Nibbio, Ferruccio
AU - Caetani, Giulia
AU - Augello, Giovanni
AU - Mian, Ornella
AU - Tuzzi, Cristina
AU - Averna, Eva
AU - Parisio, Cinzia
AU - Liuzzi, Antonio
PY - 2008/4
Y1 - 2008/4
N2 - Objective - The objective of this paper is to describe the effects of a rehabilitation programme in obese patients affected with chronic ischaemic heart disease; to identify the factors that influence weight loss and improvement in exercise capacity in everyday practice. Methods and results - We studied 562 white patients (381 men) who followed a 23.3 ± 3.9 days in-hospital programme. They attended daily sessions of aerobic activity (cycloergometer, walking, and strength exercise); a low-calorie diet was set at approximately 80% of resting energy expenditure. By the end of the programme BMI decreased from 38.0 ± 4.9 to 36.7 ± 4.8 kg/m2 (P <0.001). Attained metabolic equivalents (METs) increased from 6.2 ± 2.5 METs to 7.3 ± 2.7 (P <0.001). Age, sex, presence of diabetes and education level were significantly related to the outcomes. Patients who took beta-blockers and statins had less BMI improvement: -1.2 ± 0.7 kg/m2 vs.-1.4 ± 0.6 (P = 0.013) and -1.3 ± 0.6 vs. -1.4 ± 0.7 (P = 0.023), respectively. Patients that took diuretics and angiotensin receptor blockers (ARB) had less improvement in exercise capacity: 0.9 ± 1.0 METS vs. 1.3 ± 1.3 (P <0.001) and 0.8 ± 1.3 vs. 1.2 ± 1.3 (P = 0.011), respectively. After a median interval of 358 days, 152 patients were seen at a follow-up visit: their BMI increased by 1.0 ± 2.4 kg/m 2 and only 21% of patients lost weight. Conclusions - Rehabilitation improves exercise capacity and induces significant weight loss in obese patients with stable IHD, but women, diabetic, elderly and poorly educated subjects obtained unsatisfactory results. Use of diuretics and ARB seem to worsen the results. At follow-up only a small percentage of patients further improves BMI.
AB - Objective - The objective of this paper is to describe the effects of a rehabilitation programme in obese patients affected with chronic ischaemic heart disease; to identify the factors that influence weight loss and improvement in exercise capacity in everyday practice. Methods and results - We studied 562 white patients (381 men) who followed a 23.3 ± 3.9 days in-hospital programme. They attended daily sessions of aerobic activity (cycloergometer, walking, and strength exercise); a low-calorie diet was set at approximately 80% of resting energy expenditure. By the end of the programme BMI decreased from 38.0 ± 4.9 to 36.7 ± 4.8 kg/m2 (P <0.001). Attained metabolic equivalents (METs) increased from 6.2 ± 2.5 METs to 7.3 ± 2.7 (P <0.001). Age, sex, presence of diabetes and education level were significantly related to the outcomes. Patients who took beta-blockers and statins had less BMI improvement: -1.2 ± 0.7 kg/m2 vs.-1.4 ± 0.6 (P = 0.013) and -1.3 ± 0.6 vs. -1.4 ± 0.7 (P = 0.023), respectively. Patients that took diuretics and angiotensin receptor blockers (ARB) had less improvement in exercise capacity: 0.9 ± 1.0 METS vs. 1.3 ± 1.3 (P <0.001) and 0.8 ± 1.3 vs. 1.2 ± 1.3 (P = 0.011), respectively. After a median interval of 358 days, 152 patients were seen at a follow-up visit: their BMI increased by 1.0 ± 2.4 kg/m 2 and only 21% of patients lost weight. Conclusions - Rehabilitation improves exercise capacity and induces significant weight loss in obese patients with stable IHD, but women, diabetic, elderly and poorly educated subjects obtained unsatisfactory results. Use of diuretics and ARB seem to worsen the results. At follow-up only a small percentage of patients further improves BMI.
KW - Exercise tolerance
KW - Ischaemic heart disease
KW - Obesity
KW - Weight loss
UR - http://www.scopus.com/inward/record.url?scp=42249083932&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=42249083932&partnerID=8YFLogxK
U2 - 10.2143/AC.63.2.2029521
DO - 10.2143/AC.63.2.2029521
M3 - Article
C2 - 18468193
AN - SCOPUS:42249083932
VL - 63
SP - 153
EP - 159
JO - Acta Cardiologica
JF - Acta Cardiologica
SN - 0001-5385
IS - 2
ER -