Short-term efficacy of Narivent® in the treatment of nasal congestion

Valerio Damiani, Angelo Camaioni, Claudio Viti, Giulia Schillani, Francesca Foltran, Antonella Silvia Scirè, Giada Morpurgo, Dario Gregori

Research output: Contribution to journalArticlepeer-review

Abstract

Rationale and aim: Nasal congestion is a common symptom in rhinologic diseases such as rhinosinusitis, nasal polyposis and adenoid pathology. Although various pharmacotherapy options exist, no agent is universally efficacious. The aim of this study was to evaluate the efficacy of Narivent®, an osmotically acting medical device with antioedematous and anti-inflammatory effects, in a short-term (7days) treatment. Methods: A single-centre prospective study with a pre-post design was conducted with consecutive enrolment in an Italian Otolaryngology Department of 36 both genders patients with nasal congestion. Patients received 2 puffs of Narivent® into each nostril 2 times a day over the course of 1 week. The severity of symptoms was assessed subjectively as measured by a 0 to 10 visual analogue scale (VAS) and the presence/absence of symptoms and signs. Differences in subjective and objective severity measures before and after treatment were compared using Paired-Sample Wilcoxon Signed Rank Test. Results: A significant improvement after treatment (p

Original languageEnglish
Pages (from-to)66-72
Number of pages7
JournalOpen Medical Devices Journal
Volume4
Issue numberSPL. ISS.
DOIs
Publication statusPublished - 2012

Keywords

  • Anti-inflammatory activity
  • Anti-oedematous activity
  • Nasal congestion
  • Osmotically acting medical device

ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine (miscellaneous)

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