Short-term reproducibility of nocturnal non-dipping pattern in recently diagnosed essential hypertensives

C. Cuspidi, G. Macca, I. Michev, M. Salerno, V. Fusi, B. Severgnini, C. Corti, S. Meani, C. Valerio, F. Magrini, A. Zanchetti

Research output: Contribution to journalArticle

Abstract

Objective: To investigate in a selected population of patients with a recently diagnosed essential hypertension the short-term intrasubject variability of diurnal changes in blood pressure (BP). Methods: Two hundred and eight consecutive, recently diagnosed, never treated essential hypertensives (119 men, 89 women, 46 ± 12 years) underwent 24-h ambulatory BP monitoring (ABPM) twice within 3 weeks. Dipping pattern was defined as a reduction in average systolic and diastolic BP at night greater than 10% compared to average daytime values. Results: 177 subjects (85%) showed no change in their diurnal variations in BP. Of the 159 subjects who had a dipping pattern on first ABPM, 134 (90.6%) confirmed this type of profile on the second ABPM, while 15 (9.4%) showed a non-dipping pattern. Of the 59 subjects who had a non-dipping pattern on the first ABPM, 43 (72.2%) confirmed their initial profile on the second ABPM, while 16 (28.8%) did not. Conclusion: These findings indicate that short-term reproducibility of diurnal changes in BP in early phases of untreated essential hypertension, characterized by a large prevalence of dipping pattern, is overall satisfactory. However, our study underlines that also in this particularly selected population of hypertensives the definition of non-dipping status on the basis of a single ABPM remains unreliable in about one-third of patients.

Original languageEnglish
Pages (from-to)79-83
Number of pages5
JournalBlood Pressure
Volume11
Issue number2
DOIs
Publication statusPublished - 2002

Keywords

  • Ambulatory blood pressure monitoring
  • Hypertension
  • Non-dipping pattern
  • Reproducibility

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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    Cuspidi, C., Macca, G., Michev, I., Salerno, M., Fusi, V., Severgnini, B., Corti, C., Meani, S., Valerio, C., Magrini, F., & Zanchetti, A. (2002). Short-term reproducibility of nocturnal non-dipping pattern in recently diagnosed essential hypertensives. Blood Pressure, 11(2), 79-83. https://doi.org/10.1080/08037050211255