Short-term side-effects of brain MR examination at 7 T: A single-centre experience

M. Cosottini, D. Frosini, L. Biagi, I. Pesaresi, M. Costagli, G. Tiberi, M. Symms, M. Tosetti

Research output: Contribution to journalArticle

Abstract

Objective: To study patient tolerability of brain imaging that employs an ultrahigh field (7 T) MR system. Methods: We examined 180 subjects that underwent brain MR examination at 7 T. A tolerability test consisting of two parts (during patient table motion and during the examination) was administered to all subjects in order to monitor their discomfort. The scores range from 0 to 5 for the first part, and from 0 to 10 for the second part, the total score of each subject therefore ranging from 0 (no side effects reported) to 15 (lowest tolerability). Results: A total of 51 % of subjects reported at least one side effect but all were mild in intensity and did not require examination interruption. No serious adverse event was reported. The total score (mean ± standard deviation) was 1.1 ± 1.5 out of 15 (mean score 0.4 ± 0.7 out of 5 during patient table motion and 0.7 ± 1.1 out of 10 during MR). Patient discomfort was not related to gender or health status, but it was reduced with time after system installation with increasing operator experience in performing UHF MR examinations. Conclusions: Ultrahigh field MRI is well tolerated without excessive discomfort to subjects. • 7-T MRI is well tolerated with low incidence of side effects • The subjects' discomfort during 7-T MRI is reduced as the operators' experience increases • 7-T MRI is practicable in healthy subjects and patients with neurodegenerative diseases.

Original languageEnglish
Pages (from-to)1923-1928
Number of pages6
JournalEuropean Radiology
Volume24
Issue number8
DOIs
Publication statusPublished - 2014

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Brain
Neuroimaging
Neurodegenerative Diseases
Health Status
Healthy Volunteers
Incidence

Keywords

  • 7 T
  • Magnetic resonance imaging
  • Prospective study
  • Side effects
  • Tolerability

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Short-term side-effects of brain MR examination at 7 T : A single-centre experience. / Cosottini, M.; Frosini, D.; Biagi, L.; Pesaresi, I.; Costagli, M.; Tiberi, G.; Symms, M.; Tosetti, M.

In: European Radiology, Vol. 24, No. 8, 2014, p. 1923-1928.

Research output: Contribution to journalArticle

Cosottini, M. ; Frosini, D. ; Biagi, L. ; Pesaresi, I. ; Costagli, M. ; Tiberi, G. ; Symms, M. ; Tosetti, M. / Short-term side-effects of brain MR examination at 7 T : A single-centre experience. In: European Radiology. 2014 ; Vol. 24, No. 8. pp. 1923-1928.
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AU - Frosini, D.

AU - Biagi, L.

AU - Pesaresi, I.

AU - Costagli, M.

AU - Tiberi, G.

AU - Symms, M.

AU - Tosetti, M.

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AB - Objective: To study patient tolerability of brain imaging that employs an ultrahigh field (7 T) MR system. Methods: We examined 180 subjects that underwent brain MR examination at 7 T. A tolerability test consisting of two parts (during patient table motion and during the examination) was administered to all subjects in order to monitor their discomfort. The scores range from 0 to 5 for the first part, and from 0 to 10 for the second part, the total score of each subject therefore ranging from 0 (no side effects reported) to 15 (lowest tolerability). Results: A total of 51 % of subjects reported at least one side effect but all were mild in intensity and did not require examination interruption. No serious adverse event was reported. The total score (mean ± standard deviation) was 1.1 ± 1.5 out of 15 (mean score 0.4 ± 0.7 out of 5 during patient table motion and 0.7 ± 1.1 out of 10 during MR). Patient discomfort was not related to gender or health status, but it was reduced with time after system installation with increasing operator experience in performing UHF MR examinations. Conclusions: Ultrahigh field MRI is well tolerated without excessive discomfort to subjects. • 7-T MRI is well tolerated with low incidence of side effects • The subjects' discomfort during 7-T MRI is reduced as the operators' experience increases • 7-T MRI is practicable in healthy subjects and patients with neurodegenerative diseases.

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