Abstract
The stimulation of RNA synthesis induced by estradiol was studied on 60 breast cancers in short-term cultures. In the same tumors the estrogen receptor (ER) assay was carried out. In 35% of the cases studied the stimulating effect by estradiol in vitro was observed. The frequency of response to in vitro hormone treatment was higher (42%) in ER+ cancers and lower (25%) in ER-cancers. The specificity of the in vitro test was assessed by the use of tamoxifen.
Original language | English |
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Pages (from-to) | 2365-2369 |
Number of pages | 5 |
Journal | Cancer |
Volume | 43 |
Issue number | 6 |
Publication status | Published - 1979 |
ASJC Scopus subject areas
- Cancer Research
- Oncology