Should Lactobacillus sporogenes and Bacillus coagulans have a future?

L. Drago, E. De Vecchi

Research output: Contribution to journalArticlepeer-review


Probiotics are gaining increasing scientific and commercial interest as functional foods. Their success has led to the development and marketing of a broad range of products based on probiotics. In this context, resolution of the taxonomy of microbial species remains a key point, since different species belonging to the same genus may have different beneficial properties. Lactobacillus sporogenes, which should be correctly classified as Bacillus coagulans, represents the archetypal misidentified probiotic and its inclusion among probiotics has often been a matter of debate. Since this bacterium shows characteristics of both genera Lactobacillus and Bacillus, its taxonomic position between the families Lactobacillaceae and Bacillaceae has often been discussed. This review summarizes the salient probiotic features of L. sporogenes/B. coagulans by examining currently available information. Although the use of L sporogenes spores as a probiotic has increased in recent years, clinical evidence of its benefits are limited to only a few studies involving small patient populations.

Original languageEnglish
Pages (from-to)371-377
Number of pages7
JournalJournal of Chemotherapy
Issue number4
Publication statusPublished - Aug 2009


  • Bacillus coagulans
  • Bacterial taxonomy
  • Lacobacillus sporogenes
  • Probiotics

ASJC Scopus subject areas

  • Infectious Diseases
  • Oncology
  • Pharmacology (medical)
  • Pharmacology

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