Sick Sinus Syndrome

Roberto De Ponti, Jacopo Marazzato, Giuseppe Bagliani, Fabio M. Leonelli, Luigi Padeletti

Research output: Chapter in Book/Report/Conference proceedingChapter


The sick sinus syndrome includes symptoms and signs related to sinus node dysfunction. This can be caused by intrinsic abnormal impulse formation and/or propagation from the sinus node or, in some cases, by extrinsic reversible causes. Careful evaluation of symptoms and of the electrocardiogram is of crucial importance, because diagnosis is mainly based on these 2 elements. In some cases, the pathophysiologic mechanism that induces sinus node dysfunction also favors the onset of atrial arrhythmias, which results in a more complex clinical condition, known as “bradycardia-tachycardia syndrome.”

Original languageEnglish
Title of host publicationCardiac Electrophysiology Clinics
EditorsPierre COLINET, Pierre LAMBERT
PublisherW.B. Saunders Ltd
Number of pages13
ISBN (Print)9780323610520
Publication statusPublished - Jun 1 2018


  • Bradycardia
  • Bradycardia-tachycardia syndrome
  • Sick sinus syndrome
  • Sinoatrial block
  • Sinus arrest
  • Sinus node
  • Sinus node dysfunction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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