SIGNIFICATO DEI CALONI EPIDERMICI NEI MECCANISMI DI OMEOSTASI CUTANEA

Translated title of the contribution: Significance of epidermal chalones in the mechanisms of cutaneous homeostasis

F. Sala, C. Crosti, S. Menni

Research output: Contribution to journalArticlepeer-review

Abstract

The epidermal homeostatic mechanisms are the key to the scientific and rational interpretation of epidermal pathology. Bullough, who discovered epidermal chalone, made an essential contribution to this. There are two kinds of chalones inhibiting epidermal cell proliferation: G1 and G2 chalone. They are proteins or glycoproteins produced by epidermal cells. Their action is strengthened by adrenaline and glycocorticoids which would act by means of reducing the dermal cell production of epidermal chalone inhibitor. This provides interesting prospects in tumoral pathology.

Translated title of the contributionSignificance of epidermal chalones in the mechanisms of cutaneous homeostasis
Original languageItalian
Pages (from-to)543-546
Number of pages4
JournalGiornale Italiano di Dermatologia e Venereologia
Volume115
Issue number11-12
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Dermatology

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