Significance of the effective remnant liver volume in major hepatectomies

Salvatore Gruttadauria, Fabio Vasta, Marta Ida Minervini, Tommaso Piazza, Antonio Arcadipane, Amadeo Marcos, Bruno Gridelli

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The aim of this study is to identify the minimum safe amount of effective remnant liver volume (ERLV) in patients undergoing a major hepatectomy. Thirty-eight consecutive major hepatectomies (resection of ≥3 Couinaud segments) performed between July 1999 and March 2004 in which a frozen section liver biopsy was obtained were included. No patient had chronic viral hepatitis, cirrhosis, or cholestasis. The total liver volume (TLV) was calculated using the Vauthey formula, and the postsurgical liver volume (PSLV) was derived by subtracting the estimated volume of liver resected from the TLV. The PSLV minus the percentage of macrovesicular steatosis as nonfunctional liver was defined as the effective remnant liver volume (ERLV). Three groups of ERLV/TLV ratios (60%) were correlated with liver resection type, mortality, complications, intraoperative blood transfusions, operative time, length of hospitalization, and mean value of liver function tests in the first 5 postoperative days. Comparisons between clinical parameters were performed by Pearson X2 test. There was significant correlation between ERLV/TLV ratios and surgical resection type (P <0.001), early postoperative mortality (P <0.01), and complications (P <0.003). The ERLV/TLV ratio may be a useful predictor of surgical outcome after major hepatectomy.

Original languageEnglish
Pages (from-to)235-240
Number of pages6
JournalAmerican Surgeon
Volume71
Issue number3
Publication statusPublished - 2005

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Hepatectomy
Liver
Mortality
Liver Function Tests
Cholestasis
Intraoperative Complications
Frozen Sections
Chronic Hepatitis
Operative Time
Blood Transfusion

ASJC Scopus subject areas

  • Surgery

Cite this

Gruttadauria, S., Vasta, F., Minervini, M. I., Piazza, T., Arcadipane, A., Marcos, A., & Gridelli, B. (2005). Significance of the effective remnant liver volume in major hepatectomies. American Surgeon, 71(3), 235-240.

Significance of the effective remnant liver volume in major hepatectomies. / Gruttadauria, Salvatore; Vasta, Fabio; Minervini, Marta Ida; Piazza, Tommaso; Arcadipane, Antonio; Marcos, Amadeo; Gridelli, Bruno.

In: American Surgeon, Vol. 71, No. 3, 2005, p. 235-240.

Research output: Contribution to journalArticle

Gruttadauria, S, Vasta, F, Minervini, MI, Piazza, T, Arcadipane, A, Marcos, A & Gridelli, B 2005, 'Significance of the effective remnant liver volume in major hepatectomies', American Surgeon, vol. 71, no. 3, pp. 235-240.
Gruttadauria, Salvatore ; Vasta, Fabio ; Minervini, Marta Ida ; Piazza, Tommaso ; Arcadipane, Antonio ; Marcos, Amadeo ; Gridelli, Bruno. / Significance of the effective remnant liver volume in major hepatectomies. In: American Surgeon. 2005 ; Vol. 71, No. 3. pp. 235-240.
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