Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer

Mario Testini, Piero Portincasa, Giuseppe Piccinni, Germana Lissidini, Fabio Pellegrini, Luigi Greco

Research output: Contribution to journalArticle

Abstract

Aim: To evaluate the main factors associated with mortality in patients undergoing surgery for perforated peptic ulcer referred to an academic department of general surgery in a large southern Italian city. Methods: One hundred and forty-nine consecutive patients (M:F ratio=110:39, mean age 52 yrs, range 16-95) with peptic ulcer disease were investigated for clinical history (including age, sex, previous history of peptic ulcer, associated diseases, delayed abdominal surgery, ulcer site, operation type, shock on admission, postoperative general complications, and intra-abdominal and/or wound infections), serum analyses and radiological findings. Results: The overall mortality rate was 4.0 %. Among all factors, an age above 65 years, one or more associated diseases, delayed abdominal surgery, shock on admission, postoperative abdominal complications and/or wound infections, were significantly associated (χ2) with increased mortality in patients undergoing surgery (0.0001

Original languageEnglish
Pages (from-to)2338-2340
Number of pages3
JournalWorld Journal of Gastroenterology
Volume9
Issue number10
Publication statusPublished - Oct 2003

ASJC Scopus subject areas

  • Gastroenterology

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    Testini, M., Portincasa, P., Piccinni, G., Lissidini, G., Pellegrini, F., & Greco, L. (2003). Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer. World Journal of Gastroenterology, 9(10), 2338-2340.