Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study

M. Diomedi, F. Sallustio, B. Rizzato, F. Ferrante, G. Leone, E. Spera, M. Scarfini, G. Bernardi

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The authors performed a double-blind, placebo-controlled study in 28 patients to evaluate the effects of sildenafil on cerebral hemodynamics. A significant improvement of cerebrovascular reactivity, without any modification of other variables, was recorded 1 hour after the administration of 50 mg sildenafil. Further investigations are needed to evaluate whether cerebrovascular reactivity improvement could contribute to triggering sildenafil-induced migraine.

Original languageEnglish
Pages (from-to)919-921
Number of pages3
JournalNeurology
Volume65
Issue number6
DOIs
Publication statusPublished - Sep 27 2005

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Migraine Disorders
Hemodynamics
Placebos
Sildenafil Citrate

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Diomedi, M., Sallustio, F., Rizzato, B., Ferrante, F., Leone, G., Spera, E., ... Bernardi, G. (2005). Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study. Neurology, 65(6), 919-921. https://doi.org/10.1212/01.wnl.0000173835.12308.bb

Sildenafil increases cerebrovascular reactivity : A transcranial Doppler study. / Diomedi, M.; Sallustio, F.; Rizzato, B.; Ferrante, F.; Leone, G.; Spera, E.; Scarfini, M.; Bernardi, G.

In: Neurology, Vol. 65, No. 6, 27.09.2005, p. 919-921.

Research output: Contribution to journalArticle

Diomedi, M, Sallustio, F, Rizzato, B, Ferrante, F, Leone, G, Spera, E, Scarfini, M & Bernardi, G 2005, 'Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study', Neurology, vol. 65, no. 6, pp. 919-921. https://doi.org/10.1212/01.wnl.0000173835.12308.bb
Diomedi M, Sallustio F, Rizzato B, Ferrante F, Leone G, Spera E et al. Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study. Neurology. 2005 Sep 27;65(6):919-921. https://doi.org/10.1212/01.wnl.0000173835.12308.bb
Diomedi, M. ; Sallustio, F. ; Rizzato, B. ; Ferrante, F. ; Leone, G. ; Spera, E. ; Scarfini, M. ; Bernardi, G. / Sildenafil increases cerebrovascular reactivity : A transcranial Doppler study. In: Neurology. 2005 ; Vol. 65, No. 6. pp. 919-921.
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