Abstract
The authors performed a double-blind, placebo-controlled study in 28 patients to evaluate the effects of sildenafil on cerebral hemodynamics. A significant improvement of cerebrovascular reactivity, without any modification of other variables, was recorded 1 hour after the administration of 50 mg sildenafil. Further investigations are needed to evaluate whether cerebrovascular reactivity improvement could contribute to triggering sildenafil-induced migraine.
| Original language | English |
|---|---|
| Pages (from-to) | 919-921 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 65 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Sep 27 2005 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Sildenafil increases cerebrovascular reactivity : A transcranial Doppler study. / Diomedi, M.; Sallustio, F.; Rizzato, B.; Ferrante, F.; Leone, G.; Spera, E.; Scarfini, M.; Bernardi, G.
In: Neurology, Vol. 65, No. 6, 27.09.2005, p. 919-921.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sildenafil increases cerebrovascular reactivity
T2 - A transcranial Doppler study
AU - Diomedi, M.
AU - Sallustio, F.
AU - Rizzato, B.
AU - Ferrante, F.
AU - Leone, G.
AU - Spera, E.
AU - Scarfini, M.
AU - Bernardi, G.
PY - 2005/9/27
Y1 - 2005/9/27
N2 - The authors performed a double-blind, placebo-controlled study in 28 patients to evaluate the effects of sildenafil on cerebral hemodynamics. A significant improvement of cerebrovascular reactivity, without any modification of other variables, was recorded 1 hour after the administration of 50 mg sildenafil. Further investigations are needed to evaluate whether cerebrovascular reactivity improvement could contribute to triggering sildenafil-induced migraine.
AB - The authors performed a double-blind, placebo-controlled study in 28 patients to evaluate the effects of sildenafil on cerebral hemodynamics. A significant improvement of cerebrovascular reactivity, without any modification of other variables, was recorded 1 hour after the administration of 50 mg sildenafil. Further investigations are needed to evaluate whether cerebrovascular reactivity improvement could contribute to triggering sildenafil-induced migraine.
UR - http://www.scopus.com/inward/record.url?scp=25444473998&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=25444473998&partnerID=8YFLogxK
U2 - 10.1212/01.wnl.0000173835.12308.bb
DO - 10.1212/01.wnl.0000173835.12308.bb
M3 - Article
C2 - 16051646
AN - SCOPUS:25444473998
VL - 65
SP - 919
EP - 921
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 6
ER -