Abstract
The authors performed a double-blind, placebo-controlled study in 28 patients to evaluate the effects of sildenafil on cerebral hemodynamics. A significant improvement of cerebrovascular reactivity, without any modification of other variables, was recorded 1 hour after the administration of 50 mg sildenafil. Further investigations are needed to evaluate whether cerebrovascular reactivity improvement could contribute to triggering sildenafil-induced migraine.
| Original language | English |
|---|---|
| Pages (from-to) | 919-921 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 65 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Sep 27 2005 |
ASJC Scopus subject areas
- Neuroscience(all)
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Cite this
Diomedi, M., Sallustio, F., Rizzato, B., Ferrante, F., Leone, G., Spera, E., Scarfini, M., & Bernardi, G. (2005). Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study. Neurology, 65(6), 919-921. https://doi.org/10.1212/01.wnl.0000173835.12308.bb