Silent ischaemia in post-myocardial infarction patients submitted to physical training

C. Opasich, F. Cobelli, C. Farilla, G. Riccardi, L. Bosco, M. T. La Rovere, E. Bramucci, G. Specchia

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Recently, more attention has been focused on the detection and treatment of silent myocardial ischaemia. Electrocardiographic signs of exercise-induced asymptomatic myocardial ischaemia are very common findings among survivors of acute myocardial infarction. From data of our population we found that silent exercise-induced ischaemia is present in 15-20% of all patients, and that about half of the patients with exercise-induced ST-segment depression were free of symptoms. Ergometric data at the ischaemic threshold are similar between asymptomatic and symptomatic patients while the presence of symptoms is more frequent in patients who were also symptomatic before the myocardial infarction. During the training period, the majority of the 'silent' patients remained asymptomatic, 23% developed effort angina, and 9% developed angina at rest. Training monitoring may be helpful in identifying the variability of symptoms. Physical training, in particular an intermittent programme, increased the work-load at which the ECG ischaemic signs appeared. Among the possible mechanisms responsible for exercise-induced silent ischaemia, a different pain tolerance and control of analgesia may be ascribed to explain the absence of pain, perhaps also determined by different endogenous beta-endorphin levels.

Original languageEnglish
Pages (from-to)22-27
Number of pages6
JournalEuropean Heart Journal
Volume9
Issue numberSUPPL. M
Publication statusPublished - 1988

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Ischemia
Myocardial Infarction
Exercise
Myocardial Ischemia
Pain
beta-Endorphin
Unstable Angina
Workload
Analgesia
Survivors
Electrocardiography
Population
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Opasich, C., Cobelli, F., Farilla, C., Riccardi, G., Bosco, L., La Rovere, M. T., ... Specchia, G. (1988). Silent ischaemia in post-myocardial infarction patients submitted to physical training. European Heart Journal, 9(SUPPL. M), 22-27.

Silent ischaemia in post-myocardial infarction patients submitted to physical training. / Opasich, C.; Cobelli, F.; Farilla, C.; Riccardi, G.; Bosco, L.; La Rovere, M. T.; Bramucci, E.; Specchia, G.

In: European Heart Journal, Vol. 9, No. SUPPL. M, 1988, p. 22-27.

Research output: Contribution to journalArticle

Opasich, C, Cobelli, F, Farilla, C, Riccardi, G, Bosco, L, La Rovere, MT, Bramucci, E & Specchia, G 1988, 'Silent ischaemia in post-myocardial infarction patients submitted to physical training', European Heart Journal, vol. 9, no. SUPPL. M, pp. 22-27.
Opasich C, Cobelli F, Farilla C, Riccardi G, Bosco L, La Rovere MT et al. Silent ischaemia in post-myocardial infarction patients submitted to physical training. European Heart Journal. 1988;9(SUPPL. M):22-27.
Opasich, C. ; Cobelli, F. ; Farilla, C. ; Riccardi, G. ; Bosco, L. ; La Rovere, M. T. ; Bramucci, E. ; Specchia, G. / Silent ischaemia in post-myocardial infarction patients submitted to physical training. In: European Heart Journal. 1988 ; Vol. 9, No. SUPPL. M. pp. 22-27.
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