Silicone lymphadenopathy: Presentation of a further case containing asteroid bodies on fine-needle cytology sample

Maria Gabriella Malzone, Anna Cipolletta Campanile, Antonella Gioioso, Alfredo Fucito, Giuseppe D'Aiuto, Gerardo Botti, Franco Fulciniti

Research output: Contribution to journalArticle

Abstract

Silicone lymphadenopathy is a recognized complication of breast augmentation. It is thought to occur when silicone droplets migrate from breast implants to lymph nodes. We report the cytologic findings in axillary and inguinal lymph node aspirate smears from a 35-year-old Italian woman, who came to our observation 10 years after bilateral cosmetic breast augmentation. A fine-needle cytology of the axillary lymph node showed extensive granulomatous inflammation, numerous histiocytes, and multinucleated giant cells containing star-shaped structures known as "asteroid bodies." The inguinal lymph node aspirate simply showed an aspecific reactive hyperplasia. No evidence of malignancy was present in any of the smears as well as in the excised axillary lymph node.

Original languageEnglish
Pages (from-to)57-59
Number of pages3
JournalDiagnostic Cytopathology
Volume43
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

Keywords

  • Asteroid bodies
  • Breast augmentation
  • Fine-needle cytology
  • Lymph node
  • Silicone lymphadenopathy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Medicine(all)

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