Silver nitrate for Kaposi’s sarcoma nodules: A new look at an old treatment

Lucia Brambilla, Athanasia Tourlaki

Research output: Contribution to journalArticle

Abstract

Introduction: Fungating classic Kaposi’s sarcoma (KS) tumors represent a therapeutic challenge given the increased risk of resistance to traditional local chemotherapy and the frequent concomitant skin infections. Objective: To study the effect and tolerability of silver nitrate cauterization in patients with fungating KS tumors. Methods: A single arm, prospective study in patients with soft, fungating and/or oozing KS tumors cauterized with silver nitrate sticks. The application was repeated once every three weeks until the lesion became fibrous or after two consecutive applications without any clinical improvement. Results: Eleven patients (10 males, one female, mean age of 75.8 years) with at least one fungating KS tumor of the lower limbs were treated. Complete or partial resolution of the KS lesion was achieved in 91% of patients after an average of 2.1 treatments (range, 1–4 treatments). Conclusions: Fungating KS tumors can be treated simply, effectively and safely in the office with silver nitrate cauterization.

Original languageEnglish
Pages (from-to)152-154
Number of pages3
JournalJournal of Dermatological Treatment
Volume28
Issue number2
DOIs
Publication statusPublished - 2017

Keywords

  • fungating nodule
  • Kaposi’s sarcoma
  • silver nitrate cauterization
  • treatment

ASJC Scopus subject areas

  • Dermatology

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