Simplifying clinical risk prediction for percutaneous coronary intervention of bifurcation lesions: The case for the ACEF (age, creatinine, ejection fraction) score

Giuseppe Biondi-Zoccai, Enrico Romagnoli, Davide Castagno, Imad Sheiban, Stefano De Servi, Corrado Tamburino, Antonio Colombo, Francesco Burzotta, Patrizia Presbitero, Leonardo Bolognese, Leonardo Paloscia, Paolo Rubino, Gennaro Sardella, Carlo Briguori, Luigi Niccoli, Gianfranco Franco, Domenico D. Di Girolamo, Luigi Piatti, Cesare Greco, A. Sonia PetronioBruno Loi, Alberto Benassi, Aldo Patti, Achille Gaspardone, Giacomo Frati, Giuseppe Sangiorgi

Research output: Contribution to journalArticle

Abstract

Aims: We aimed to appraise the predictive accuracy of a novel and user-friendly risk score, the ACEF (age, creatinine, ejection fraction), in patients undergoing PCI for coronary bifurcations. Methods and results: A multicentre, retrospective study was conducted enrolling consecutive patients undergoing bifurcation PCI between January 2002 and December 2006 in 22 Italian centres. Patients with complete data to enable computation of the ACEF score were divided into three groups according to tertiles of ACEF score. The primary endpoint was 30-day mortality. The discrimination of the ACEF score as a continuous variable was also appraised with area under the curve (AUC) of the receiver-operating characteristic. A total of 3,535 patients were included: 1,119 in the lowest tertile of ACEF score, 1,190 in the mid tertile, and 1,153 in the highest tertile. Increased ACEF score was associated with significantly different rates of 30-day mortality (0.1% in the lowest tertile vs. 0.5% in the mid tertile and 3.0% in the highest tertile, p

Original languageEnglish
Pages (from-to)359-367
Number of pages9
JournalEuroIntervention
Volume8
Issue number3
DOIs
Publication statusPublished - Jul 2012

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Keywords

  • Bifurcation
  • Coronary artery disease
  • Prognosis
  • Risk score
  • Stent

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Biondi-Zoccai, G., Romagnoli, E., Castagno, D., Sheiban, I., De Servi, S., Tamburino, C., Colombo, A., Burzotta, F., Presbitero, P., Bolognese, L., Paloscia, L., Rubino, P., Sardella, G., Briguori, C., Niccoli, L., Franco, G., Di Girolamo, D. D., Piatti, L., Greco, C., ... Sangiorgi, G. (2012). Simplifying clinical risk prediction for percutaneous coronary intervention of bifurcation lesions: The case for the ACEF (age, creatinine, ejection fraction) score. EuroIntervention, 8(3), 359-367. https://doi.org/10.4244/EIJV8I3A55