Simulating the interactions among vasomotion waves of peripheral vascular districts

Giuseppe Baselli, A. Porta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Simulations are performed in order to analyze the tendency of oscillating peripheral vascular districts (PVDs) to maintain equal phases thus inducing low frequency (LF) waves in systemic arterial pressure (AP). A PVD model regulating the local flow by means of a delayed non-linear feedback displayed spontaneous oscillations with a 12 sec period in the pressure range (40 -150 mmHg) of active flow compensation. Two identical PVDs loading the same Windkessel compartment could oscillate in phase inducing significant (10% of mean) AP waves; however, this behavior was unstable. On the contrary, phase opposition (without AP waves) was stable and corresponded to an energetic minimum (-9% compared to the unstable solution). The introduction of either baroreflex mechanisms or a central drive was able to steadily align the PVD phases. Vasomotion synchronization can be a powerful modulation mechanism of LF waves in systemic AP.

Original languageEnglish
Title of host publicationComputers in Cardiology
EditorsA. Murray
Pages49-52
Number of pages4
Volume29
Publication statusPublished - 2002
EventComputers in Cardiology 2002 - Memphis, TN, United States
Duration: Sep 22 2002Sep 25 2002

Other

OtherComputers in Cardiology 2002
CountryUnited States
CityMemphis, TN
Period9/22/029/25/02

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ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

Cite this

Baselli, G., & Porta, A. (2002). Simulating the interactions among vasomotion waves of peripheral vascular districts. In A. Murray (Ed.), Computers in Cardiology (Vol. 29, pp. 49-52)