HCV infection is usually diagnosed by means of an enzyme immune assay for the detection of antibody against HCV. The window period between infection and seroconversion remains a dramatic problem in the transfusional and diagnostic setting. In this chapter, we report (i) procedures for assays using two different approaches designed to reduce the window period and (ii) performance in terms of specificity and sensitivity in the detection of both antibody and antigen, and we compare their efficacy with that of commercial assays.
|Number of pages||9|
|Journal||Methods in molecular biology (Clifton, N.J.)|
|Publication status||Published - 2009|
ASJC Scopus subject areas
- Molecular Biology