Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child

Paolo D'Angelo, Antonella Grigoli, Angela Rita Sementa, Serena Tropia, Rita Alaggio, Maurizio Aricò

Research output: Contribution to journalArticle

Abstract

We report the case of a 3-year-old girl with a mediastinal mass, severe anemia, leukocytosis and neutropenia, in whom, after initial suspicion of metastatic neuroblastoma, a final diagnosis of concurrent ganglioneuroblastoma and acute lymphoblastic leukemia was made. The mediastinal tumor was surgically excised and the child subsequently underwent chemotherapy for acute lymphoblastic leukemia. The patient remains in complete remission from both diseases 4 years after the diagnosis and 24 months after completion of all treatment. The simultaneous occurrence of 2 different neoplasms in a child is very infrequent, and no comparable cases are reported in the literature.

Original languageEnglish
Pages (from-to)72-75
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume34
Issue number1
DOIs
Publication statusPublished - Jan 2012

Fingerprint

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Ganglioneuroblastoma
Leukocytosis
Neutropenia
Neuroblastoma
Anemia
Neoplasms
Drug Therapy
Therapeutics

Keywords

  • acute lymphoblastic leukemia
  • childhood cancer
  • ganglioneuroblastoma
  • neuroblastoma
  • simultaneous diagnosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child. / D'Angelo, Paolo; Grigoli, Antonella; Sementa, Angela Rita; Tropia, Serena; Alaggio, Rita; Aricò, Maurizio.

In: Journal of Pediatric Hematology/Oncology, Vol. 34, No. 1, 01.2012, p. 72-75.

Research output: Contribution to journalArticle

D'Angelo, Paolo ; Grigoli, Antonella ; Sementa, Angela Rita ; Tropia, Serena ; Alaggio, Rita ; Aricò, Maurizio. / Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child. In: Journal of Pediatric Hematology/Oncology. 2012 ; Vol. 34, No. 1. pp. 72-75.
@article{25efab04737a439a894053adb3421a50,
title = "Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child",
abstract = "We report the case of a 3-year-old girl with a mediastinal mass, severe anemia, leukocytosis and neutropenia, in whom, after initial suspicion of metastatic neuroblastoma, a final diagnosis of concurrent ganglioneuroblastoma and acute lymphoblastic leukemia was made. The mediastinal tumor was surgically excised and the child subsequently underwent chemotherapy for acute lymphoblastic leukemia. The patient remains in complete remission from both diseases 4 years after the diagnosis and 24 months after completion of all treatment. The simultaneous occurrence of 2 different neoplasms in a child is very infrequent, and no comparable cases are reported in the literature.",
keywords = "acute lymphoblastic leukemia, childhood cancer, ganglioneuroblastoma, neuroblastoma, simultaneous diagnosis",
author = "Paolo D'Angelo and Antonella Grigoli and Sementa, {Angela Rita} and Serena Tropia and Rita Alaggio and Maurizio Aric{\`o}",
year = "2012",
month = "1",
doi = "10.1097/MPH.0b013e31820db67b",
language = "English",
volume = "34",
pages = "72--75",
journal = "Journal of Pediatric Hematology/Oncology",
issn = "1077-4114",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child

AU - D'Angelo, Paolo

AU - Grigoli, Antonella

AU - Sementa, Angela Rita

AU - Tropia, Serena

AU - Alaggio, Rita

AU - Aricò, Maurizio

PY - 2012/1

Y1 - 2012/1

N2 - We report the case of a 3-year-old girl with a mediastinal mass, severe anemia, leukocytosis and neutropenia, in whom, after initial suspicion of metastatic neuroblastoma, a final diagnosis of concurrent ganglioneuroblastoma and acute lymphoblastic leukemia was made. The mediastinal tumor was surgically excised and the child subsequently underwent chemotherapy for acute lymphoblastic leukemia. The patient remains in complete remission from both diseases 4 years after the diagnosis and 24 months after completion of all treatment. The simultaneous occurrence of 2 different neoplasms in a child is very infrequent, and no comparable cases are reported in the literature.

AB - We report the case of a 3-year-old girl with a mediastinal mass, severe anemia, leukocytosis and neutropenia, in whom, after initial suspicion of metastatic neuroblastoma, a final diagnosis of concurrent ganglioneuroblastoma and acute lymphoblastic leukemia was made. The mediastinal tumor was surgically excised and the child subsequently underwent chemotherapy for acute lymphoblastic leukemia. The patient remains in complete remission from both diseases 4 years after the diagnosis and 24 months after completion of all treatment. The simultaneous occurrence of 2 different neoplasms in a child is very infrequent, and no comparable cases are reported in the literature.

KW - acute lymphoblastic leukemia

KW - childhood cancer

KW - ganglioneuroblastoma

KW - neuroblastoma

KW - simultaneous diagnosis

UR - http://www.scopus.com/inward/record.url?scp=84855440722&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855440722&partnerID=8YFLogxK

U2 - 10.1097/MPH.0b013e31820db67b

DO - 10.1097/MPH.0b013e31820db67b

M3 - Article

C2 - 21646915

AN - SCOPUS:84855440722

VL - 34

SP - 72

EP - 75

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

IS - 1

ER -