Simultaneous EEG-fMRI for functional neurological assessment

Giulia Mele, Carlo Cavaliere, Vincenzo Alfano, Mario Orsini, Marco Salvatore, Marco Aiello

Research output: Contribution to journalReview articlepeer-review


The increasing incidence of neurodegenerative and psychiatric diseases requires increasingly sophisticated tools for their diagnosis and monitoring. Clinical assessment takes advantage of objective parameters extracted by electroencephalogram and magnetic resonance imaging (MRI) among others, to support clinical management of neurological diseases. The complementarity of these two tools can be now emphasized by the possibility of integrating the two technologies in a hybrid solution, allowing simultaneous acquisition of the two signals by the novel EEG-fMRI technology. This review will focus on simultaneous EEG-fMRI technology and related early studies, dealing about issues related to the acquisition and processing of simultaneous signals, and including critical discussion about clinical and technological perspectives.

Original languageEnglish
Article numbere00848
JournalFrontiers in Neurology
Issue numberJUL
Publication statusPublished - Jan 1 2019


  • EEG
  • EEG spectra
  • FMRI
  • Functional connectivity
  • Multimodal image analysis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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