Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis

Muhammad Nabeel Anwar, Laura Bonzano, Davide Rossi-Sebastiano, Luca Roccatagliata, Giovanni Gualniera, Paolo Vitali, Vittorio Sanguineti, Pietro Morasso, Fabio Bandini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Multiple sclerosis (MS) is a chronic, inflammatory disease that affects the central nervous system and causes gradual destruction of myelin. Inflammation of the optic nerve (optic neuritis, ON) is a common symptom at the onset of MS. Visual evoked potentials (VEPs) have been widely used as diagnostic tools for ON as they can detect the malfunctioning of visual pathways. Functional Magnetic Resonance Imaging (fMRI) has also been used to identify impaired visual brain function in ON patients. As VEPs and fMRI have complementary features (high temporal resolution and high spatial resolution, respectively), the integration of simultaneously recorded VEP and fMRI might provide more detailed information on the cortical representation of the visual stimulus, thus improving the diagnosis of ON. In this work, we present a method for simultaneous acquisition of EEG signals and fMRI. More specifically, we show that reliable VEPs can be obtained during fMRI acquisition and, conversely, sequences of MR images of good quality can be obtained in presence of EEG electrodes in the MRI bore. On the basis of these preliminary results, we suggest that the simultaneous recording of VEP and fMRI is feasible and can be used in studying ON.

Original languageEnglish
Title of host publicationProceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007
Pages197-202
Number of pages6
Publication statusPublished - 2007
Event5th IASTED International Conference on Biomedical Engineering, BioMED 2007 - Innsbruck, Austria
Duration: Feb 14 2007Feb 16 2007

Other

Other5th IASTED International Conference on Biomedical Engineering, BioMED 2007
CountryAustria
CityInnsbruck
Period2/14/072/16/07

Keywords

  • Electroencephalography (EEG)
  • Functional magnetic resonance imaging (fMRI)
  • Optic neuritis (ON)
  • Visual evoked potentials (VEPs)

ASJC Scopus subject areas

  • Biomedical Engineering

Fingerprint Dive into the research topics of 'Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis'. Together they form a unique fingerprint.

  • Cite this

    Anwar, M. N., Bonzano, L., Rossi-Sebastiano, D., Roccatagliata, L., Gualniera, G., Vitali, P., Sanguineti, V., Morasso, P., & Bandini, F. (2007). Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis. In Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007 (pp. 197-202)