Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis

Muhammad Nabeel Anwar, Laura Bonzano, Davide Rossi-Sebastiano, Luca Roccatagliata, Giovanni Gualniera, Paolo Vitali, Vittorio Sanguineti, Pietro Morasso, Fabio Bandini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Multiple sclerosis (MS) is a chronic, inflammatory disease that affects the central nervous system and causes gradual destruction of myelin. Inflammation of the optic nerve (optic neuritis, ON) is a common symptom at the onset of MS. Visual evoked potentials (VEPs) have been widely used as diagnostic tools for ON as they can detect the malfunctioning of visual pathways. Functional Magnetic Resonance Imaging (fMRI) has also been used to identify impaired visual brain function in ON patients. As VEPs and fMRI have complementary features (high temporal resolution and high spatial resolution, respectively), the integration of simultaneously recorded VEP and fMRI might provide more detailed information on the cortical representation of the visual stimulus, thus improving the diagnosis of ON. In this work, we present a method for simultaneous acquisition of EEG signals and fMRI. More specifically, we show that reliable VEPs can be obtained during fMRI acquisition and, conversely, sequences of MR images of good quality can be obtained in presence of EEG electrodes in the MRI bore. On the basis of these preliminary results, we suggest that the simultaneous recording of VEP and fMRI is feasible and can be used in studying ON.

Original languageEnglish
Title of host publicationProceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007
Pages197-202
Number of pages6
Publication statusPublished - 2007
Event5th IASTED International Conference on Biomedical Engineering, BioMED 2007 - Innsbruck, Austria
Duration: Feb 14 2007Feb 16 2007

Other

Other5th IASTED International Conference on Biomedical Engineering, BioMED 2007
CountryAustria
CityInnsbruck
Period2/14/072/16/07

Fingerprint

Bioelectric potentials
Optics
Electroencephalography
Neurology
Magnetic resonance imaging
Magnetic Resonance Imaging
Brain
Electrodes

Keywords

  • Electroencephalography (EEG)
  • Functional magnetic resonance imaging (fMRI)
  • Optic neuritis (ON)
  • Visual evoked potentials (VEPs)

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Anwar, M. N., Bonzano, L., Rossi-Sebastiano, D., Roccatagliata, L., Gualniera, G., Vitali, P., ... Bandini, F. (2007). Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis. In Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007 (pp. 197-202)

Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis. / Anwar, Muhammad Nabeel; Bonzano, Laura; Rossi-Sebastiano, Davide; Roccatagliata, Luca; Gualniera, Giovanni; Vitali, Paolo; Sanguineti, Vittorio; Morasso, Pietro; Bandini, Fabio.

Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007. 2007. p. 197-202.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Anwar, MN, Bonzano, L, Rossi-Sebastiano, D, Roccatagliata, L, Gualniera, G, Vitali, P, Sanguineti, V, Morasso, P & Bandini, F 2007, Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis. in Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007. pp. 197-202, 5th IASTED International Conference on Biomedical Engineering, BioMED 2007, Innsbruck, Austria, 2/14/07.
Anwar MN, Bonzano L, Rossi-Sebastiano D, Roccatagliata L, Gualniera G, Vitali P et al. Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis. In Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007. 2007. p. 197-202
Anwar, Muhammad Nabeel ; Bonzano, Laura ; Rossi-Sebastiano, Davide ; Roccatagliata, Luca ; Gualniera, Giovanni ; Vitali, Paolo ; Sanguineti, Vittorio ; Morasso, Pietro ; Bandini, Fabio. / Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis. Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007. 2007. pp. 197-202
@inproceedings{35deef5dc46e4def970db3987886224a,
title = "Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis",
abstract = "Multiple sclerosis (MS) is a chronic, inflammatory disease that affects the central nervous system and causes gradual destruction of myelin. Inflammation of the optic nerve (optic neuritis, ON) is a common symptom at the onset of MS. Visual evoked potentials (VEPs) have been widely used as diagnostic tools for ON as they can detect the malfunctioning of visual pathways. Functional Magnetic Resonance Imaging (fMRI) has also been used to identify impaired visual brain function in ON patients. As VEPs and fMRI have complementary features (high temporal resolution and high spatial resolution, respectively), the integration of simultaneously recorded VEP and fMRI might provide more detailed information on the cortical representation of the visual stimulus, thus improving the diagnosis of ON. In this work, we present a method for simultaneous acquisition of EEG signals and fMRI. More specifically, we show that reliable VEPs can be obtained during fMRI acquisition and, conversely, sequences of MR images of good quality can be obtained in presence of EEG electrodes in the MRI bore. On the basis of these preliminary results, we suggest that the simultaneous recording of VEP and fMRI is feasible and can be used in studying ON.",
keywords = "Electroencephalography (EEG), Functional magnetic resonance imaging (fMRI), Optic neuritis (ON), Visual evoked potentials (VEPs)",
author = "Anwar, {Muhammad Nabeel} and Laura Bonzano and Davide Rossi-Sebastiano and Luca Roccatagliata and Giovanni Gualniera and Paolo Vitali and Vittorio Sanguineti and Pietro Morasso and Fabio Bandini",
year = "2007",
language = "English",
pages = "197--202",
booktitle = "Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007",

}

TY - GEN

T1 - Simultaneous recording of Vep and fMRI to study optic neuritis in multiple sclerosis

AU - Anwar, Muhammad Nabeel

AU - Bonzano, Laura

AU - Rossi-Sebastiano, Davide

AU - Roccatagliata, Luca

AU - Gualniera, Giovanni

AU - Vitali, Paolo

AU - Sanguineti, Vittorio

AU - Morasso, Pietro

AU - Bandini, Fabio

PY - 2007

Y1 - 2007

N2 - Multiple sclerosis (MS) is a chronic, inflammatory disease that affects the central nervous system and causes gradual destruction of myelin. Inflammation of the optic nerve (optic neuritis, ON) is a common symptom at the onset of MS. Visual evoked potentials (VEPs) have been widely used as diagnostic tools for ON as they can detect the malfunctioning of visual pathways. Functional Magnetic Resonance Imaging (fMRI) has also been used to identify impaired visual brain function in ON patients. As VEPs and fMRI have complementary features (high temporal resolution and high spatial resolution, respectively), the integration of simultaneously recorded VEP and fMRI might provide more detailed information on the cortical representation of the visual stimulus, thus improving the diagnosis of ON. In this work, we present a method for simultaneous acquisition of EEG signals and fMRI. More specifically, we show that reliable VEPs can be obtained during fMRI acquisition and, conversely, sequences of MR images of good quality can be obtained in presence of EEG electrodes in the MRI bore. On the basis of these preliminary results, we suggest that the simultaneous recording of VEP and fMRI is feasible and can be used in studying ON.

AB - Multiple sclerosis (MS) is a chronic, inflammatory disease that affects the central nervous system and causes gradual destruction of myelin. Inflammation of the optic nerve (optic neuritis, ON) is a common symptom at the onset of MS. Visual evoked potentials (VEPs) have been widely used as diagnostic tools for ON as they can detect the malfunctioning of visual pathways. Functional Magnetic Resonance Imaging (fMRI) has also been used to identify impaired visual brain function in ON patients. As VEPs and fMRI have complementary features (high temporal resolution and high spatial resolution, respectively), the integration of simultaneously recorded VEP and fMRI might provide more detailed information on the cortical representation of the visual stimulus, thus improving the diagnosis of ON. In this work, we present a method for simultaneous acquisition of EEG signals and fMRI. More specifically, we show that reliable VEPs can be obtained during fMRI acquisition and, conversely, sequences of MR images of good quality can be obtained in presence of EEG electrodes in the MRI bore. On the basis of these preliminary results, we suggest that the simultaneous recording of VEP and fMRI is feasible and can be used in studying ON.

KW - Electroencephalography (EEG)

KW - Functional magnetic resonance imaging (fMRI)

KW - Optic neuritis (ON)

KW - Visual evoked potentials (VEPs)

UR - http://www.scopus.com/inward/record.url?scp=56149108733&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=56149108733&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:56149108733

SP - 197

EP - 202

BT - Proceedings of the 5th IASTED International Conference on Biomedical Engineering, BioMED 2007

ER -