Simultaneous tumors: Acute myeloid leukemia infiltrating mediastinal ganglioneuroblastoma

Andrea Di Cataldo, Katia Mazzocco, Gaetano Magro, Elena Mirabile, Luca Lo Nigro, Raffaella Defferrari, Gian Paolo Tonini

Research output: Contribution to journalArticlepeer-review


We report the case of a child presenting with concurrent thoracic ganglioneuroblastoma and acute myeloid leukemia. The peculiarity was the close relation between the two tumors with the latter infiltrating the former one. Histological and genomic studies indicate the different clonal origins of the malignancies in the patient, and we hypothesized that GNB and AML developed independently. Our observation suggests that in patients with more than one tumor, though discovered at different times, one neoplasm is not always secondary.

Original languageEnglish
Pages (from-to)298-300
Number of pages3
JournalPediatric Blood and Cancer
Issue number2
Publication statusPublished - Feb 2011


  • AML
  • Neuroblastoma
  • Pediatric hematology/oncology

ASJC Scopus subject areas

  • Oncology
  • Pediatrics, Perinatology, and Child Health
  • Hematology


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