TY - JOUR
T1 - Simultaneous vs. sequential biventricular pacing in dilated cardiomyopathy
T2 - An acute hemodynamic study
AU - Perego, Giovanni B.
AU - Chianca, Roberto
AU - Facchini, Mario
AU - Frattola, Alessandra
AU - Balla, Eva
AU - Zucchi, Stefania
AU - Cavaglià, Sergio
AU - Vicini, Ilaria
AU - Negretto, Marco
AU - Osculati, Giuseppe
PY - 2003
Y1 - 2003
N2 - Aims: Simultaneous biventricular pacing improves left ventricular (LV) systolic performance in patients with dilated cardiomyopathy and intraventricular conduction delay. We tested the hypothesis that further improvements can be obtained using sequential biventricular pacing by optimizing both atrioventricular and interventricular delays. Methods and results: In 12 patients, LV pressure, right ventricular (RV) pressure and respective rates of change of pressure (dP/dt) were acutely measured during biventricular pacing with different atrioventricular and interventricular (VVi) intervals ranging from -60 to +40 ms. The average increase vs. baseline in maximum LV dP/dt was higher for sequential than for simultaneous biventricular pacing (VDD mode: 35±20 vs. 29±18%, P
AB - Aims: Simultaneous biventricular pacing improves left ventricular (LV) systolic performance in patients with dilated cardiomyopathy and intraventricular conduction delay. We tested the hypothesis that further improvements can be obtained using sequential biventricular pacing by optimizing both atrioventricular and interventricular delays. Methods and results: In 12 patients, LV pressure, right ventricular (RV) pressure and respective rates of change of pressure (dP/dt) were acutely measured during biventricular pacing with different atrioventricular and interventricular (VVi) intervals ranging from -60 to +40 ms. The average increase vs. baseline in maximum LV dP/dt was higher for sequential than for simultaneous biventricular pacing (VDD mode: 35±20 vs. 29±18%, P
KW - Cardiac resynchronization therapy
KW - Heart failure
KW - Hemodynamics
KW - Pacing
KW - Sequential biventricular pacing
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U2 - 10.1016/S1388-9842(02)00204-0
DO - 10.1016/S1388-9842(02)00204-0
M3 - Article
C2 - 12798828
AN - SCOPUS:0042941894
VL - 5
SP - 305
EP - 313
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
SN - 1388-9842
IS - 3
ER -