Simultaneous vs. sequential biventricular pacing in dilated cardiomyopathy: An acute hemodynamic study

Giovanni B. Perego, Roberto Chianca, Mario Facchini, Alessandra Frattola, Eva Balla, Stefania Zucchi, Sergio Cavaglià, Ilaria Vicini, Marco Negretto, Giuseppe Osculati

Research output: Contribution to journalArticlepeer-review

Abstract

Aims: Simultaneous biventricular pacing improves left ventricular (LV) systolic performance in patients with dilated cardiomyopathy and intraventricular conduction delay. We tested the hypothesis that further improvements can be obtained using sequential biventricular pacing by optimizing both atrioventricular and interventricular delays. Methods and results: In 12 patients, LV pressure, right ventricular (RV) pressure and respective rates of change of pressure (dP/dt) were acutely measured during biventricular pacing with different atrioventricular and interventricular (VVi) intervals ranging from -60 to +40 ms. The average increase vs. baseline in maximum LV dP/dt was higher for sequential than for simultaneous biventricular pacing (VDD mode: 35±20 vs. 29±18%, P

Original languageEnglish
Pages (from-to)305-313
Number of pages9
JournalEuropean Journal of Heart Failure
Volume5
Issue number3
DOIs
Publication statusPublished - 2003

Keywords

  • Cardiac resynchronization therapy
  • Heart failure
  • Hemodynamics
  • Pacing
  • Sequential biventricular pacing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Simultaneous vs. sequential biventricular pacing in dilated cardiomyopathy: An acute hemodynamic study'. Together they form a unique fingerprint.

Cite this