Single bone metastasis from adenocarcinoma of the lacrimal gland: A case report

Marianna Ricci, Elena Amadori, Fausto Chiesa, Alberto Bongiovanni, Chiara Liverani, Laura Fabbri, Maria Cristina Falasconi, Roberto Casadei, Devil Oboldi, Riccardo Galassi, Simona Micheletti, Stefano Severi, Luigi Serra, Federica Pieri, Luca Calabrese, Nada Riva, Sebastiano Calpona, Erica Gunelli, Laura Mercatali, Dino AmadoriToni Ibrahim

Research output: Contribution to journalArticlepeer-review


Malignant tumors of the lacrimal gland are rare, and single bone metastases from lacrimal gland carcinoma are an exceptional event. We present the case of a 71-year-old man with a history of lumbar pain and left exophthalmos. Surgical resection of the lacrimal lesion and a bone biopsy gave a final histopathological diagnosis of primary ductal adenocarcinoma of the lacrimal gland with bone metastasis. The pathological tissue from both procedures was positive for androgen receptor expression. The patient underwent embolization and radiotherapy in association with total androgen blockade. After 20 months, the patient is still asymptomatic and has maintained the partial response at L1 with no progression to other sites. Our patient would appear to have a better prognosis and the disease a more indolent clinical course than the other cases of ductal adenocarcinoma of the lacrimal gland reported in the literature.

Original languageEnglish
Pages (from-to)1735-1739
Number of pages5
JournalFuture Oncology
Issue number10
Publication statusPublished - Aug 1 2014


  • androgen receptor
  • androgen receptor blockade
  • bone metastasis
  • ductal adenocarcinoma
  • lacrimal gland tumor

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Medicine(all)


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