Single Center Five Years’ Experience of Ozaki Procedure: Midterm Follow-up

Sergio Pirola, Giorgio Mastroiacovo, Francesco Giuseppe Arlati, Giulia Mostardini, Alice Bonomi, Eleonora Penza, Gianluca Polvani

Research output: Contribution to journalArticlepeer-review


Background: The Ozaki procedure is an innovative surgical technique aiming at the reconstruction of the aortic valve with autologous pericardium to overcome the limitations of commercially available prostheses. Methods: We retrospectively analyzed 71 patients who underwent the Ozaki operation at our center between October 2014 and February 2020. Results: No in-hospital death occurred. Freedom from major adverse valve-related events was 97%. The aortic gradients and transvalvular velocity were significantly lower at the 3-month echocardiographic control than at the predischarge echocardiography (10.93 ± 5.38, P < .01 vs 16.24 ± 7.67, P < .01, respectively). The median follow-up period was 20.7 months (range, 2 to 47). Four patients showed mild/moderate aortic insufficiency (5.6%), and none showed severe aortic valve insufficiency. No patients underwent reoperation. Conclusions: Midterm outcome follow-up of the Ozaki procedure showed optimal results in terms of mortality, transaortic valve gradients, freedom from major adverse valve-related events, and recurrence of aortic valve insufficiency.

Original languageEnglish
JournalAnnals of Thoracic Surgery
Publication statusAccepted/In press - 2021

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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