Single photon emission computed tomography study of human pulmonary perfusion: Preliminary findings

L. Carratu, M. Salvatore, V. Lopez-Majano, M. Sofia, P. Muto, G. Ariemma

Research output: Contribution to journalArticlepeer-review

Abstract

Single photon emission computed tomography (SPECT) was performed with99Tcm-albumin macroaggregates to study human pulmonary perfusion in healthy subjects and patients with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and lung neoplasms. The reconstructed SPECT data was displayed in coronal, transverse, sagittal plane sections and compared to conventional perfusion scans. The SPECT data gave more complicated anatomical information about the extent of damage and morphology of the pulmonary vascular bed. In healthy subjects and COPD patients, qualitative and quantitative assessment of pulmonary perfusion could be obtained from serial SPECT scans with respect to distribution and relative concentration of the injected radiopharmaceutical. Furthermore, SPECT of pulmonary perfusion has been useful in detecting the extent of damage to the pulmonary circulation.This is useful for the preoperative evaluation and staging of lung cancer.

Original languageEnglish
Pages (from-to)91-99
Number of pages9
JournalNuclear Medicine Communications
Volume5
Issue number2
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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