Single-Pill Combination of Telmisartan/Amlodipine in Patients With Severe Hypertension: Results From the TEAMSTA Severe HTN Study

Joel M. Neutel, Giusepe Mancia, Henry R. Black, Bjorn Dahlöf, Holly Defeo, Ludwin Ley, Richard Vinisko, T. Donova, N. Gotcheva, S. Milanov, V. Mincheva, G. Pencheva, N. Zlatareva, D. Raev, S. Stoimenov, S. Petranov, I. Horný, O. Jerábek, I. Karen, J. C. KucharZ. Krumlov Lorenc, J. Nagel, M. Peterka, E. Zídková, F. Barucq, A. Queguiner, F. Robin, P. Touzet, M. Bismuth, M. Bourgoin, C. Giraldi, N. Breton, R. Combet, G. Venturini, P. Causse, F. Henriot, A. Khennouf, D. Lecaignard, P. Cayron, P. Chalaux, A. Chaleon, A. Chalvignac, B. D. Forestier, J. C. Deme, C. Fivel, M. Depoisier, B. Dimon, M. Flosi, A. MacAgno, M. Ripoll, O. Geronimi, B. Michalak, B. Geoffray, E. Hannoush, J. P. Jacquet, L. Jappy, E. Jordan, F. Lacoin, D. Lefort, B. Lemarie, G. Martocq, P. Michellier, E. Nabedian, C. A. Percheron, B. Perrin, M. Pouget, J. J. Roger, G. Rouviere, D. Sacareau, D. Taminau, M. H. Vuong, D. Zimmermann, V. András, T. Lívia, P. Ferenc, N. Gabriella, I. László, P. Ibolya, S. Judit, Z. Károly, R. Judit, I. Benedek, M. Cristea, G. P. Tatu-Chitoiu, S. Dragulescu, D. Gaita, C. A. Georgescu, B. Minescu, I. Manitiu, A. Matei, A. M. Salajan, G. Aroutiounov, I. Gordeev, A. Ivleva, A. Martynov, V. Zadionchenko, A. Filippov, B. Goloshchekin, V. Kostenko, M. Repin, T. Tyurina, A. Vishnevsky, S. H. Baek, S. M. Kang, H. M. Kwon, C. G. Park, M. H. Kim, M. Y. Lee, J. Y. Yang, J. Gonsorcík, S. Hojerová, M. Hranai, V. Kolíková, L. Ruffini, P. Záreczky, B. Gil-Extremera, J. Munoz, J. Oliván, F. Pont, J. L. Tovar, A. Faynyk, B. Goloborodko, V. Shatilo, Y. Sirenko, Y. Svyshchenko, I. Vykhovanyuk, L. Yena, O. Karpenko, L. Kononenko, O. Korzh, I. Kraiz, N. Bittar, D. G. Cheung, K. Crump, J. L. Diaz, R. L. Eddy, R. D. Eyzaguirre, R. J. Graf, J. M. Hill, D. B. Jack, L. Jagminas, B. Kanna, Y. Khronusova, P. J. Lane, L. Levinson, R. Marple, C. J. Mello, N. R. Patel, A. Patron, J. L. Pool, E. B. Portnoy, H. A. Punzi, D. R. Ricci, M. B. Samson, S. Slabic, R. Struble, R. E. Tidman, J. Wayne, D. E. Webster, N. Winer, B. Zehnder

Research output: Contribution to journalArticlepeer-review

Abstract

This 8-week, randomized, double-blind, controlled study compared efficacy and tolerability of telmisartan/amlodipine (T/A) single-pill combination (SPC) vs the respective monotherapies in 858 patients with severe hypertension (systolic/diastolic blood pressure [SBP/DBP] ≥180/95 mmHg). At 8weeks, T/A provided significantly greater reductions from baseline in seated trough cuff SBP/DBP (-47.5mmHg/-18.7mmHg) vs T (P

Original languageEnglish
Pages (from-to)206-215
Number of pages10
JournalJournal of clinical hypertension (Greenwich, Conn.)
Volume14
Issue number4
DOIs
Publication statusPublished - Apr 2012

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism

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