Sinusoidal obstruction syndrome/veno-occlusive disease: Current situation and perspectives - A position statement from the European Society for Blood and Marrow Transplantation (EBMT)

M. Mohty, F. Malard, M. Abecassis, E. Aerts, A. S. Alaskar, M. Aljurf, M. Arat, P. Bader, F. Baron, A. Bazarbachi, D. Blaise, F. Ciceri, S. Corbacioglu, J. H. Dalle, R. F. Duarte, T. Fukuda, A. Huynh, T. Masszi, M. Michallet, A. NaglerM. Nichonghaile, T. Pagluica, C. Peters, F. B. Petersen, P. G. Richardson, T. Ruutu, B. N. Savani, E. Wallhult, I. Yakoub-Agha, E. Carreras

Research output: Contribution to journalArticle

Abstract

Sinusoidal obstruction syndrome or veno-occlusive disease (SOS/VOD) is a potentially life-threatening complication of hematopoietic SCT (HSCT). This review aims to highlight, on behalf of the European Society for Blood and Marrow Transplantation, the current knowledge on SOS/VOD pathophysiology, risk factors, diagnosis and treatments. Our perspectives on SOS/VOD are (i) to accurately identify its risk factors; (ii) to define new criteria for its diagnosis; (III) to search for SOS/VOD biomarkers and (iv) to propose prospective studies evaluating SOS/VOD prevention and treatment in adults and children.

Original languageEnglish
Pages (from-to)781-789
Number of pages9
JournalBone Marrow Transplantation
Volume50
Issue number6
DOIs
Publication statusPublished - Jun 4 2015

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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    Mohty, M., Malard, F., Abecassis, M., Aerts, E., Alaskar, A. S., Aljurf, M., Arat, M., Bader, P., Baron, F., Bazarbachi, A., Blaise, D., Ciceri, F., Corbacioglu, S., Dalle, J. H., Duarte, R. F., Fukuda, T., Huynh, A., Masszi, T., Michallet, M., ... Carreras, E. (2015). Sinusoidal obstruction syndrome/veno-occlusive disease: Current situation and perspectives - A position statement from the European Society for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplantation, 50(6), 781-789. https://doi.org/10.1038/bmt.2015.52