Size of sentinel-node metastasis and chances of non-sentinel-node involvement and survival in early stage vulvar cancer: Results from GROINSS-V, a multicentre observational study

M. H. Oonk, B. M. van Hemel, H. Hollema, J. A. de Hullu, A. C. Ansink, I. Vergote, R. H. Verheijen, A. Maggioni, K. N. Gaarenstroom, P. J. Baldwin, E. B. van Dorst, J. van der Velden, R. H. Hermans, H. W. van der Putten, P. Drouin, I. B. Runnebaum, W. J. Sluiter, A. G. van der Zee

Research output: Contribution to journalArticle

Abstract

Background: Currently, all patients with vulvar cancer with a positive sentinel node undergo inguinofemoral lymphadenectomy, irrespective of the size of sentinel-node metastases. Our study aimed to assess the association between size of sentinel-node metastasis and risk of metastases in non-sentinel nodes, and risk of disease-specific survival in early stage vulvar cancer. Methods: In the GROningen INternational Study on Sentinel nodes in Vulvar cancer (GROINSS-V), sentinel-node detection was done in patients with T1-T2 (

Original languageEnglish
Pages (from-to)646-652
Number of pages7
JournalThe Lancet Oncology
Volume11
Issue number7
DOIs
Publication statusPublished - Jul 2010

ASJC Scopus subject areas

  • Oncology

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    Oonk, M. H., van Hemel, B. M., Hollema, H., de Hullu, J. A., Ansink, A. C., Vergote, I., Verheijen, R. H., Maggioni, A., Gaarenstroom, K. N., Baldwin, P. J., van Dorst, E. B., van der Velden, J., Hermans, R. H., van der Putten, H. W., Drouin, P., Runnebaum, I. B., Sluiter, W. J., & van der Zee, A. G. (2010). Size of sentinel-node metastasis and chances of non-sentinel-node involvement and survival in early stage vulvar cancer: Results from GROINSS-V, a multicentre observational study. The Lancet Oncology, 11(7), 646-652. https://doi.org/10.1016/S1470-2045(10)70104-2