Skin picking disorder in 97 Italian and Spanish Cri du chat patients

Marianna Spunton, Andrea Guala, Maria E. Liverani, Luisa Medolago, Fabio Tognon, Félix Casado, Marta del Valle, Josefina Porras, Isabel Larrea, Giovanni Porta, Giovanni Albani, Julian Nevado, Cesare Danesino

Research output: Contribution to journalArticle

Abstract

Skin picking (SP) disorder is characterized by recurrent SP resulting in skin lesions. Several studies estimated its prevalence as approximately 2–4 % of the general population. It is also present in a high percentage of patients with intellectual and developmental disabilities, such as Cri du chat (CdC) syndrome, a rare genetic disorder caused by variable size deletions of the short arm of chromosome 5. The aim of this study was to evaluate, in 97 patients with CdC syndrome, the following data: frequency of SP, patient's age at onset, type, and topographic–anatomic distribution of the lesions presented. The results show that 85% of patients confirm a SP disorder, usually concentrated on the hands, fingers, and the face, with onset between 6 and 10 years of age, regardless of patient's sex. Evidence for early appearance of SP behavior, high prevalence in stressful circumstances, and efficacy of distracting actions immediately suggest the possibility that proper parental information about SP behavior and parental education concerning the methods to deal with this problem may result in its efficient reduction already in childhood.

Original languageEnglish
JournalAmerican Journal of Medical Genetics, Part A
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Skin
Cri-du-Chat Syndrome
Developmental Disabilities
Chromosomes, Human, Pair 5
Inborn Genetic Diseases
Age of Onset
Intellectual Disability
Fingers
Hand
Education
Population

Keywords

  • Cri du Chat Syndrome
  • rare genetic disorder
  • skin picking

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Skin picking disorder in 97 Italian and Spanish Cri du chat patients. / Spunton, Marianna; Guala, Andrea; Liverani, Maria E.; Medolago, Luisa; Tognon, Fabio; Casado, Félix; del Valle, Marta; Porras, Josefina; Larrea, Isabel; Porta, Giovanni; Albani, Giovanni; Nevado, Julian; Danesino, Cesare.

In: American Journal of Medical Genetics, Part A, 01.01.2019.

Research output: Contribution to journalArticle

Spunton, M, Guala, A, Liverani, ME, Medolago, L, Tognon, F, Casado, F, del Valle, M, Porras, J, Larrea, I, Porta, G, Albani, G, Nevado, J & Danesino, C 2019, 'Skin picking disorder in 97 Italian and Spanish Cri du chat patients', American Journal of Medical Genetics, Part A. https://doi.org/10.1002/ajmg.a.61259
Spunton, Marianna ; Guala, Andrea ; Liverani, Maria E. ; Medolago, Luisa ; Tognon, Fabio ; Casado, Félix ; del Valle, Marta ; Porras, Josefina ; Larrea, Isabel ; Porta, Giovanni ; Albani, Giovanni ; Nevado, Julian ; Danesino, Cesare. / Skin picking disorder in 97 Italian and Spanish Cri du chat patients. In: American Journal of Medical Genetics, Part A. 2019.
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