Skull base osteomyelitis and potential cerebrovascular complications in children

Mariasavina Severino, Sidath Liyanage, Vas Novelli, Beth Cheesborough, Dawn Saunders, Roxana Gunny, Andrea Rossi

Research output: Contribution to journalArticlepeer-review


Skull base osteomyelitis is an aggressive, lifethreatening infection that can be challenging to diagnose and treat. It occurs predominantly in elderly immunocompromised patients, but it has also been reported in children with normal immunological status. Typical skul base osteomyelitis arises as a complication to ear infection mainly involving the temporal bone and is usually caused by Pseudomonas aeruginosa. Atypical or central skul base osteomyelitis originates from paranasal infections, is primarily centred on the clivus and is usually caused by Aspergillus, Pseudomonas, Salmonella or Staphylococcus species. Potential complications include retropharyngeal abscesses, cranial neuropathies, meningitis, intracranial abscesses, sinovenous thrombosis, and carotid artery involvement with or without ischemic infarcts. The purpose of this pictorial essay is to illustrate the spectrum of imaging findings and potential complications of skul base osteomyelitis.

Original languageEnglish
Pages (from-to)867-874
Number of pages8
JournalPediatric Radiology
Issue number7
Publication statusPublished - Jul 2012


  • Intracranial vascular complications
  • Lemierre syndrome
  • Skull base osteomyelitis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health

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