In 15 pts presenting with cryptogenic partial epilepsy with onset after age 15, a diagnostic napping sleep EEG including a full sleep cycle was obtained. The patients were 5 men and 10 women aged 17 to 42 (mean: 27) with epilepsy documented over 6 months to 17 years (mean: 3y7m). All pts had normal neurologic status and CT scans. The number of paroxysmal events per minute and the number of paroxysmal foci were quantified visually in each subject according to individual sleep stages. Slow wave sleep resulted in significant activation vs the waking state in all pts, especially in 5 subjects in whom the waking EEG had failed to show focal paroxysms. No significant activation was found during REM sleep. Supplementary paroxysmal foci were found in 8 (during drowsiness in 6, in stage 2 sleep in 2). However, in this adult population, sleep-induced activation was less than in a comparable population of children with cryptogenic partial epilepsy. Napping sleep EEG may be considered a useful and feasible activating procedure in the diagnosis of adult-onset cryptogenic partial epilepsies.
|Translated title of the contribution||Sleep activation profile of interictal paroxysms in adult-onset cryptogenic partial epilepsies during the afternoon nap|
|Title of host publication||Bollettino - Lega Italiana contro l'Epilessia|
|Number of pages||3|
|Publication status||Published - 1988|
ASJC Scopus subject areas
- Clinical Neurology