Sleep continuity scale in Alzheimer’s disease (SCADS): application in daily clinical practice in an Italian center for dementia

R. Manni, E. Sinforiani, M. Terzaghi, C. Rezzani, C. Zucchella

Research output: Contribution to journalArticle

Abstract

Sleep disorders can occur in many neurodegenerative disorders; in a previous paper we constructed a scale investigating sleep discontinuity/fragmentation with the aim to obtain a rapidly and easily administered tool suitable for early identification and longitudinal monitoring of sleep disturbances in Alzheimer’s disease (AD). We introduced this instrument in the daily clinical practice in a center for dementia; here we present the results of our experience. Two hundred and sixteen AD outpatients referred to the Alzheimer’s Disease Assessment Unit at the IRCCS C. Mondino National Neurological Institute, Pavia, Italy, in the period October 2012 to March 2014 were administered the scale. The questionnaire global score was correlated with measures of cognitive, functional and behavioral impairment; a significant association was found with Mini-Mental State (p = 0.005), Activities of Daily Living (p = 0.01), Neuropsychiatric Inventory (p = 0.01) and Clinical Dementia Rating (p = 0.0005). The present data indicate that the previously validated questionnaire proves to be a suitable, rapid and easy to use tool in investigating sleep quality in AD in daily clinical practice. An early identification and longitudinal monitoring of sleep disturbances in AD may improve pharmacological and non-pharmacological interventions.

Original languageEnglish
Pages (from-to)469-471
Number of pages3
JournalNeurological Sciences
Volume36
Issue number3
DOIs
Publication statusPublished - 2015

Keywords

  • Alzheimer’s disease
  • Sleep disturbances
  • Sleep questionnaire

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Medicine(all)

Fingerprint Dive into the research topics of 'Sleep continuity scale in Alzheimer’s disease (SCADS): application in daily clinical practice in an Italian center for dementia'. Together they form a unique fingerprint.

  • Cite this