Sleep disturbance is a common problem in many medical disorders, including respiratory diseases such as chronic obstructive pulmonary disease (COPD). Recurrent episodes of nocturnal arterial oxyhemoglobin desaturation, especially during rapid eye movement (REM) sleep, have been extensively described in patients with COPD. Recent studies demonstrated that the prevalence of obstructive sleep apnea (OSA) in COPD patients is similar to that observed in general population. On the contrary, sleep quality has been described to be different in patients with COPD and in age-matched healthy subjects: these patients have a higher prevalence of insomnia, excessive daytime sleepiness, and nightmares than in general population. Poor sleep quality may represent a factor in the development of chronic fatigue and reduced quality of life usually reported by patients with severe COPD. The first step in the management of sleep-disordered breathing in COPD patients is optimal treatment of the underlying disease. At the moment, long-term oxygen therapy is the first-line treatment for COPD patients who are hypoxemic during the night, but non-invasive mechanical ventilation may become more important in the future.
|Translated title of the contribution||Sleep disordered breathing in patients with chronic obstructive pulmonary disease|
|Number of pages||9|
|Journal||Rassegna di Patologia dell'Apparato Respiratorio|
|Publication status||Published - Aug 2007|
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Pulmonary and Respiratory Medicine