Sleep disturbances and semen quality in an Italian cross sectional study

Research output: Contribution to journalArticle

Abstract

Introduction: In order to obtain information about the relationship between sleep disturbances and sperm parameters, we analyzed data from a study conducted in a Italian Fertility Clinic, in men of couples seeking help for infertility. Patients and methods: Male partners with or without a medical history of reproductive organ diseases (cryptorchidism, varicocele, orchitis, testicular torsion) were eligible for the study. There were 382 men evaluated from May 2014 to November 2016, all of whom completed a self-administered questionnaire on general lifestyle habits. Then all men underwent semen analysis. A total of 382 men aged 26 to 67 years (median age 39 year interquartile range 37-42) were recruited. Main results: A total of 46.3% reported having sleep disturbances. In multivariate analysis, in absence of reproductive organ diseases, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.3, p = .01), whereas in presence of reproductive organ diseases motility A was lower in patients with early morning awakening (25.0%, IQR 15.0-35.0 vs. 40.0%, IQR 30.0-50.0, p = .001). In overweight men, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.0, p = .03). Moreover, among current smokers, patients with difficulty in initiating sleep had semen volume lower (1.5 ml, IQR 1.5-2.5 vs 3.0 ml, IQR 2.0-3.5, p = .0003) and sperm concentration higher (40 millions/ml, IQR 15-60 vs 10 millions/ml, IQR 5-50 p = .03) but total sperm count was not significant different. Conclusion: Further studies are necessary to elucidate the relationship between sleep quality and semen parameters, which may have important public health implication.

Original languageEnglish
Article number16
JournalBasic and Clinical Andrology
Volume27
Issue number1
DOIs
Publication statusPublished - Aug 21 2017

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Semen Analysis
Sleep
Cross-Sectional Studies
Semen
Spermatozoa
Orchitis
Spermatic Cord Torsion
Varicocele
Reproductive History
Cryptorchidism
Sperm Count
Sleep Initiation and Maintenance Disorders
Infertility
Habits
Fertility
Life Style
Multivariate Analysis
Public Health

Keywords

  • Sleep parameters
  • Sleep quality
  • Sperm motility
  • Sperm parameters

ASJC Scopus subject areas

  • Reproductive Medicine
  • Urology

Cite this

@article{94a900ea467e40ea84ea98d1e81d33dd,
title = "Sleep disturbances and semen quality in an Italian cross sectional study",
abstract = "Introduction: In order to obtain information about the relationship between sleep disturbances and sperm parameters, we analyzed data from a study conducted in a Italian Fertility Clinic, in men of couples seeking help for infertility. Patients and methods: Male partners with or without a medical history of reproductive organ diseases (cryptorchidism, varicocele, orchitis, testicular torsion) were eligible for the study. There were 382 men evaluated from May 2014 to November 2016, all of whom completed a self-administered questionnaire on general lifestyle habits. Then all men underwent semen analysis. A total of 382 men aged 26 to 67 years (median age 39 year interquartile range 37-42) were recruited. Main results: A total of 46.3{\%} reported having sleep disturbances. In multivariate analysis, in absence of reproductive organ diseases, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.3, p = .01), whereas in presence of reproductive organ diseases motility A was lower in patients with early morning awakening (25.0{\%}, IQR 15.0-35.0 vs. 40.0{\%}, IQR 30.0-50.0, p = .001). In overweight men, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.0, p = .03). Moreover, among current smokers, patients with difficulty in initiating sleep had semen volume lower (1.5 ml, IQR 1.5-2.5 vs 3.0 ml, IQR 2.0-3.5, p = .0003) and sperm concentration higher (40 millions/ml, IQR 15-60 vs 10 millions/ml, IQR 5-50 p = .03) but total sperm count was not significant different. Conclusion: Further studies are necessary to elucidate the relationship between sleep quality and semen parameters, which may have important public health implication.",
keywords = "Sleep parameters, Sleep quality, Sperm motility, Sperm parameters",
author = "Paola Vigan{\`o} and Francesca Chiaffarino and Viviana Bonzi and Andrea Salonia and Elena Ricci and Enrico Papaleo and Mauri, {Paola Agnese} and Fabio Parazzini",
year = "2017",
month = "8",
day = "21",
doi = "10.1186/s12610-017-0060-0",
language = "English",
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journal = "Basic and Clinical Andrology",
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T1 - Sleep disturbances and semen quality in an Italian cross sectional study

AU - Viganò, Paola

AU - Chiaffarino, Francesca

AU - Bonzi, Viviana

AU - Salonia, Andrea

AU - Ricci, Elena

AU - Papaleo, Enrico

AU - Mauri, Paola Agnese

AU - Parazzini, Fabio

PY - 2017/8/21

Y1 - 2017/8/21

N2 - Introduction: In order to obtain information about the relationship between sleep disturbances and sperm parameters, we analyzed data from a study conducted in a Italian Fertility Clinic, in men of couples seeking help for infertility. Patients and methods: Male partners with or without a medical history of reproductive organ diseases (cryptorchidism, varicocele, orchitis, testicular torsion) were eligible for the study. There were 382 men evaluated from May 2014 to November 2016, all of whom completed a self-administered questionnaire on general lifestyle habits. Then all men underwent semen analysis. A total of 382 men aged 26 to 67 years (median age 39 year interquartile range 37-42) were recruited. Main results: A total of 46.3% reported having sleep disturbances. In multivariate analysis, in absence of reproductive organ diseases, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.3, p = .01), whereas in presence of reproductive organ diseases motility A was lower in patients with early morning awakening (25.0%, IQR 15.0-35.0 vs. 40.0%, IQR 30.0-50.0, p = .001). In overweight men, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.0, p = .03). Moreover, among current smokers, patients with difficulty in initiating sleep had semen volume lower (1.5 ml, IQR 1.5-2.5 vs 3.0 ml, IQR 2.0-3.5, p = .0003) and sperm concentration higher (40 millions/ml, IQR 15-60 vs 10 millions/ml, IQR 5-50 p = .03) but total sperm count was not significant different. Conclusion: Further studies are necessary to elucidate the relationship between sleep quality and semen parameters, which may have important public health implication.

AB - Introduction: In order to obtain information about the relationship between sleep disturbances and sperm parameters, we analyzed data from a study conducted in a Italian Fertility Clinic, in men of couples seeking help for infertility. Patients and methods: Male partners with or without a medical history of reproductive organ diseases (cryptorchidism, varicocele, orchitis, testicular torsion) were eligible for the study. There were 382 men evaluated from May 2014 to November 2016, all of whom completed a self-administered questionnaire on general lifestyle habits. Then all men underwent semen analysis. A total of 382 men aged 26 to 67 years (median age 39 year interquartile range 37-42) were recruited. Main results: A total of 46.3% reported having sleep disturbances. In multivariate analysis, in absence of reproductive organ diseases, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.3, p = .01), whereas in presence of reproductive organ diseases motility A was lower in patients with early morning awakening (25.0%, IQR 15.0-35.0 vs. 40.0%, IQR 30.0-50.0, p = .001). In overweight men, semen volume was lower in patients with difficulty in initiating sleep (2.0 ml, IQR 1.5-3.0 vs 3.0 ml, IQR 2.0-3.0, p = .03). Moreover, among current smokers, patients with difficulty in initiating sleep had semen volume lower (1.5 ml, IQR 1.5-2.5 vs 3.0 ml, IQR 2.0-3.5, p = .0003) and sperm concentration higher (40 millions/ml, IQR 15-60 vs 10 millions/ml, IQR 5-50 p = .03) but total sperm count was not significant different. Conclusion: Further studies are necessary to elucidate the relationship between sleep quality and semen parameters, which may have important public health implication.

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KW - Sperm motility

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