Translated title of the contribution: Sleep microstructure and epileptiform abnormalities in juvenile myoclonic epilepsy

E. Calia, G. Gigli, M. Diomedi, M. G. Marciani, A. Mangoni, M. G. Terzano

Research output: Contribution to journalArticlepeer-review


In 2 patients with Juvenile Myoclonic Epilepsy we analyzed the variations of epileptiform EEG abnormalities in relationship to sleep macrostructure (stage scoring according to Rechtschaffen and Kales, 1968) and to different microstructural variables (NCAP, CAP, phase A and B) in order to compare their respective sensitivity in predicting the appearance of epileptiform discharges during NREM sleep. Macrostructural analysis shows variations linked to individual epileptiform discharge rates, with a slight prevalence during slow wave sleep in both patients, without strict correlation with sleep stages. Microstructural analysis, on the contrary, indicates that the appearance of epileptiform abnormalities is clearly related to the phase A of CAP. In addition, a surprising similarity of PSW discharge rates was found during phase A in both patients. It remains controversial if epileptiform abnormalities promote CAP sequences, or, on the contrary, epileptiform discharge are provoked by phase A of CAP. In any case, microstructural analysis can add relevant information to the traditional studies on the relationship between sleep and epilepsy.

Translated title of the contributionSleep microstructure and epileptiform abnormalities in juvenile myoclonic epilepsy
Original languageItalian
Pages (from-to)175-176
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number70-71
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Clinical Neurology


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