Sleep patterns in patients with late onset partial epilepsy receiving chronic carbamazepine (CBZ) therapy

R. Manni, C. A. Galimberti, C. Zucca, L. Parietti, A. Tartara

Research output: Contribution to journalArticlepeer-review

Abstract

A night-time polygraphic sleep recording was performed in 14 patients with late onset partial epilepsy receiving chronic carbamazepine monotherapy. All patients had unstable nocturnal sleep patterns as indicated by significantly altered sleep continuity parameters compared with normal controls. Patients with poor seizure control tended to show greater alterations of sleep stability compared to patients in complete clinical remission but the difference failed to reach statistical significance. Epileptic patients also showed less REM sleep and longer REM latencies compared with normal controls, the most altered REM values being observed in patients with poor seizure control. These data confirm that polygraphic sleep alterations are seen in patients with symptomatic focal epilepsy and indicate that these abnormalities occur irrespective of seizure recurrence.

Original languageEnglish
Pages (from-to)72-76
Number of pages5
JournalEpilepsy Research
Volume7
Issue number1
DOIs
Publication statusPublished - 1990

Keywords

  • Nocturnal sleep
  • Partial epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

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