TY - JOUR
T1 - Sleep quality in renal transplant patients
T2 - A never investigated problem
AU - Sabbatini, Massimo
AU - Crispo, Anna
AU - Pisani, Antonio
AU - Gallo, Riccardo
AU - Cianciaruso, Bruno
AU - Fuiano, Giorgio
AU - Federico, Stefano
AU - Andreucci, Vittorio E.
PY - 2005/1
Y1 - 2005/1
N2 - Background. Despite the great prevalence of sleep disorders and the low quality of sleep in patients with renal diseases, to date no study has evaluated these problems in renal transplant patients. Methods. The aim of the study was to assess sleep quality (SQ) in 301 kidney graft recipients by the Pittsburgh Sleep Quality Index (PSQI, range 0-21, with higher scores indicating worse SQ), in comparison with PSQI of both patients on haemodialysis (HD) (n = 245) and normal control subjects (n = 169). Results. PSQI of renal transplant patients averaged 6.46 ± 3.71, a value significantly lower than in HD patients (8.52 ± 3.81, P <0.001), but higher than in control subjects (3.54 ± 1.61, P <0.0001 vs both transplant and dialysis patients). No correlation was found between PSQI and the main biochemical parameters of transplant patients. When the patients were divided into 'good' (PSQI <5) or 'poor' (PSQI > 5) sleepers, a significant risk of psychological problems was associated with the condition of 'poor sleeper' (OR: 2.3; P <0.02), with no further correlation detected in either of the two groups. Conclusions. These data demonstrate that SQ in renal transplant patients is surprisingly low, despite a well preserved renal function, and that poor sleep in these patients is also secondary to psychological problems. The use of PSQI in such patients represents a useful tool for the investigation of SQ and quality of life.
AB - Background. Despite the great prevalence of sleep disorders and the low quality of sleep in patients with renal diseases, to date no study has evaluated these problems in renal transplant patients. Methods. The aim of the study was to assess sleep quality (SQ) in 301 kidney graft recipients by the Pittsburgh Sleep Quality Index (PSQI, range 0-21, with higher scores indicating worse SQ), in comparison with PSQI of both patients on haemodialysis (HD) (n = 245) and normal control subjects (n = 169). Results. PSQI of renal transplant patients averaged 6.46 ± 3.71, a value significantly lower than in HD patients (8.52 ± 3.81, P <0.001), but higher than in control subjects (3.54 ± 1.61, P <0.0001 vs both transplant and dialysis patients). No correlation was found between PSQI and the main biochemical parameters of transplant patients. When the patients were divided into 'good' (PSQI <5) or 'poor' (PSQI > 5) sleepers, a significant risk of psychological problems was associated with the condition of 'poor sleeper' (OR: 2.3; P <0.02), with no further correlation detected in either of the two groups. Conclusions. These data demonstrate that SQ in renal transplant patients is surprisingly low, despite a well preserved renal function, and that poor sleep in these patients is also secondary to psychological problems. The use of PSQI in such patients represents a useful tool for the investigation of SQ and quality of life.
KW - Renal transplantation
KW - Restless legs syndrome
KW - Sleep apnea
KW - Sleep quality
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U2 - 10.1093/ndt/gfh604
DO - 10.1093/ndt/gfh604
M3 - Article
C2 - 15585511
AN - SCOPUS:13444291809
VL - 20
SP - 194
EP - 198
JO - Nephrology Dialysis Transplantation
JF - Nephrology Dialysis Transplantation
SN - 0931-0509
IS - 1
ER -