Sleepy Dialogues between Cortex and Hippocampus: Who Talks to Whom?

Giulio Tononi; Marcello Massimini; Brady A Riedner

doi:10.1016/j.neuron.2006.11.014

Sleepy Dialogues between Cortex and Hippocampus: Who Talks to Whom?

Giulio Tononi, Marcello Massimini, Brady A Riedner

Fondazione Don Carlo Gnocchi Onlus

Research output: Contribution to journal › Article

23 Citations (Scopus)

Abstract

During NREM sleep, neocortical neurons undergo near-synchronous transitions, every second or so, between UP states, during which they are depolarized and fire actively, and DOWN states, during which they are hyperpolarized and completely silent. In this issue of Neuron, Isomura et al. report that slow oscillations of membrane potential occur near-synchronously not only in neocortex but also in entorhinal cortex and subiculum. Within the hippocampus proper, pyramidal neurons lack the bistability of UP and DOWN states, but their firing is strongly modulated by cortical activity during the UP state. Intriguingly, many hippocampal neurons fire during the cortical DOWN state. Thus, during sleep UP states, the cortex can talk to the hippocampus, but it is unclear whether the hippocampus talks back.

Original language	English
Pages (from-to)	748-749
Number of pages	2
Journal	Neuron
Volume	52
Issue number	5
DOIs	https://doi.org/10.1016/j.neuron.2006.11.014
Publication status	Published - Dec 7 2006

Fingerprint

Hippocampus

Neurons

Sleep

Entorhinal Cortex

Pyramidal Cells

Neocortex

Membrane Potentials

ASJC Scopus subject areas

Neuroscience(all)

Cite this

Tononi, G., Massimini, M., & Riedner, BA. (2006). Sleepy Dialogues between Cortex and Hippocampus: Who Talks to Whom? Neuron, 52(5), 748-749. https://doi.org/10.1016/j.neuron.2006.11.014

Sleepy Dialogues between Cortex and Hippocampus : Who Talks to Whom? / Tononi, Giulio; Massimini, Marcello; Riedner, Brady A.

In: Neuron, Vol. 52, No. 5, 07.12.2006, p. 748-749.

Research output: Contribution to journal › Article

Tononi, G, Massimini, M & Riedner, BA 2006, 'Sleepy Dialogues between Cortex and Hippocampus: Who Talks to Whom?', Neuron, vol. 52, no. 5, pp. 748-749. https://doi.org/10.1016/j.neuron.2006.11.014

Tononi G, Massimini M, Riedner BA. Sleepy Dialogues between Cortex and Hippocampus: Who Talks to Whom? Neuron. 2006 Dec 7;52(5):748-749. https://doi.org/10.1016/j.neuron.2006.11.014

Tononi, Giulio ; Massimini, Marcello ; Riedner, Brady A. / Sleepy Dialogues between Cortex and Hippocampus : Who Talks to Whom?. In: Neuron. 2006 ; Vol. 52, No. 5. pp. 748-749.

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10.1016/j.neuron.2006.11.014