SLIT's Prevention of the Allergic March

Federica Porcaro, Giovanni Corsello, Giovanni Battista Pajno

Research output: Contribution to journalReview article

Abstract

PURPOSE OF REVIEW: The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age.

RECENT FINDINGS: Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease. The purpose of this manuscript is to review the latest studies addressing the effect of SLIT on the development of new sensitizations in not sensitized or already sensitized patients and progression of the allergy march.

Original languageEnglish
Pages (from-to)31
JournalCurrent Allergy and Asthma Reports
Volume18
Issue number5
DOIs
Publication statusPublished - Apr 21 2018
Externally publishedYes

Fingerprint

Sublingual Immunotherapy
Hypersensitivity
Sublingual Administration
Immunologic Desensitization
Atopic Dermatitis
Primary Prevention
Secondary Prevention
Asthma
Pediatrics
Safety
Therapeutics

Cite this

SLIT's Prevention of the Allergic March. / Porcaro, Federica; Corsello, Giovanni; Pajno, Giovanni Battista.

In: Current Allergy and Asthma Reports, Vol. 18, No. 5, 21.04.2018, p. 31.

Research output: Contribution to journalReview article

Porcaro, Federica ; Corsello, Giovanni ; Pajno, Giovanni Battista. / SLIT's Prevention of the Allergic March. In: Current Allergy and Asthma Reports. 2018 ; Vol. 18, No. 5. pp. 31.
@article{b95dac62ad5346c89b4a5efbf5f9f3f1,
title = "SLIT's Prevention of the Allergic March",
abstract = "PURPOSE OF REVIEW: The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age.RECENT FINDINGS: Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease. The purpose of this manuscript is to review the latest studies addressing the effect of SLIT on the development of new sensitizations in not sensitized or already sensitized patients and progression of the allergy march.",
author = "Federica Porcaro and Giovanni Corsello and Pajno, {Giovanni Battista}",
year = "2018",
month = "4",
day = "21",
doi = "10.1007/s11882-018-0785-7",
language = "English",
volume = "18",
pages = "31",
journal = "Current Allergy and Asthma Reports",
issn = "1529-7322",
publisher = "Current Medicine Group",
number = "5",

}

TY - JOUR

T1 - SLIT's Prevention of the Allergic March

AU - Porcaro, Federica

AU - Corsello, Giovanni

AU - Pajno, Giovanni Battista

PY - 2018/4/21

Y1 - 2018/4/21

N2 - PURPOSE OF REVIEW: The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age.RECENT FINDINGS: Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease. The purpose of this manuscript is to review the latest studies addressing the effect of SLIT on the development of new sensitizations in not sensitized or already sensitized patients and progression of the allergy march.

AB - PURPOSE OF REVIEW: The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age.RECENT FINDINGS: Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease. The purpose of this manuscript is to review the latest studies addressing the effect of SLIT on the development of new sensitizations in not sensitized or already sensitized patients and progression of the allergy march.

U2 - 10.1007/s11882-018-0785-7

DO - 10.1007/s11882-018-0785-7

M3 - Review article

C2 - 29680987

VL - 18

SP - 31

JO - Current Allergy and Asthma Reports

JF - Current Allergy and Asthma Reports

SN - 1529-7322

IS - 5

ER -