Slow cortical potentials in Parkinsonian patients during the course of an associative learning task

A. Linden, R. Bracke-Tolkmitt, W. Lutzenberger, A. G M Canavan, E. Scholz, H. C. Diener, N. Birbaumer

Research output: Contribution to journalArticle

Abstract

Twenty-one non-demented Parkinsonian patients and 21 age- and education-matched controls were compared on a neuropsychological test battery and in a forewarned reaction time (RT) task. Slow cortical potentials (SCPs) from frontal, central and parietal sites were measured in the S1-S2 interval of the RT task. The RT task included both non-learning and learning phases. The patients displayed a specific impairment in conditional learning, and in the RT task also failed to make use of conditional (arbitrary) associations to facilitate the initiation of movements. These behavioural deficits were accompanied by reduced amplitude an prolonged latency S1-processing, and by poor timing of the S1-S2 slow negative potential, which also failed to reach optimal pre-imperative levels.

Original languageEnglish
Pages (from-to)145-162
Number of pages18
JournalJournal of Psychophysiology
Volume4
Issue number2
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

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    Linden, A., Bracke-Tolkmitt, R., Lutzenberger, W., Canavan, A. G. M., Scholz, E., Diener, H. C., & Birbaumer, N. (1990). Slow cortical potentials in Parkinsonian patients during the course of an associative learning task. Journal of Psychophysiology, 4(2), 145-162.