The most recent laboratory methods on CSF are summarized and the significance of the different medical reports on normal and pathological conditions is discussed. Particular emphasis is placed on the importance of the relative increase in albumin in relation to the other proteinic fractions, especially the immunoglobulin G which is indicative of the BEE function and of the CSF turnover. The particular significance of oligoclonal distribution is considered. Reference is made to a personal case list including some cases that can be judged inflammatory and of slow development due to their chronological relation to an infectious episode or previous vaccination alternative diagnostic hypothesis in relation to a dismetabolic or tumoral or degenerative condition: a case of progressive myoclonic epilepsy following measles, a case of infantile myoclonic encephalopathy with a neurological syndrome of progressive polymorphism arising after a smallpox vaccination, a case of progressive nature of doubtful diagnosis later recorded as neuroassonal dystrophy. Finally, mention is made of the problem of interference of collateral factors on immunological CSF reports.
|Translated title of the contribution||Slowly progressive neurological conditions in children and immunological findings|
|Number of pages||6|
|Publication status||Published - 1977|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health