Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients

Fabio Fornari, Carlo Filice, Gian Ludovico Rapaccini, Eugenio Caturelli, Luigi Cavanna, Giuseppe Civardi, Michele Di Stasi, Elisabetta Buscarini, Luigi Buscarini

Research output: Contribution to journalArticle

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Abstract

Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.

Original languageEnglish
Pages (from-to)2267-2275
Number of pages9
JournalDigestive Diseases and Sciences
Volume39
Issue number10
DOIs
Publication statusPublished - Oct 1994

Fingerprint

Fine Needle Biopsy
Hepatocellular Carcinoma
Biopsy
Liver
Lymphoma
Neoplasm Metastasis
Neoplasms

Keywords

  • adenomatous hyperplasia
  • hepatocellular carcinoma
  • small hepatic lesions
  • ultrasonically guided fine-needle biopsy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Fornari, F., Filice, C., Rapaccini, G. L., Caturelli, E., Cavanna, L., Civardi, G., ... Buscarini, L. (1994). Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients. Digestive Diseases and Sciences, 39(10), 2267-2275. https://doi.org/10.1007/BF02090383

Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients. / Fornari, Fabio; Filice, Carlo; Rapaccini, Gian Ludovico; Caturelli, Eugenio; Cavanna, Luigi; Civardi, Giuseppe; Di Stasi, Michele; Buscarini, Elisabetta; Buscarini, Luigi.

In: Digestive Diseases and Sciences, Vol. 39, No. 10, 10.1994, p. 2267-2275.

Research output: Contribution to journalArticle

Fornari, F, Filice, C, Rapaccini, GL, Caturelli, E, Cavanna, L, Civardi, G, Di Stasi, M, Buscarini, E & Buscarini, L 1994, 'Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients', Digestive Diseases and Sciences, vol. 39, no. 10, pp. 2267-2275. https://doi.org/10.1007/BF02090383
Fornari, Fabio ; Filice, Carlo ; Rapaccini, Gian Ludovico ; Caturelli, Eugenio ; Cavanna, Luigi ; Civardi, Giuseppe ; Di Stasi, Michele ; Buscarini, Elisabetta ; Buscarini, Luigi. / Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients. In: Digestive Diseases and Sciences. 1994 ; Vol. 39, No. 10. pp. 2267-2275.
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