Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients

Fabio Fornari; Carlo Filice; Gian Ludovico Rapaccini; Eugenio Caturelli; Luigi Cavanna; Giuseppe Civardi; Michele Di Stasi; Elisabetta Buscarini; Luigi Buscarini

doi:10.1007/BF02090383

Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients

Fabio Fornari, Carlo Filice, Gian Ludovico Rapaccini, Eugenio Caturelli, Luigi Cavanna, Giuseppe Civardi, Michele Di Stasi, Elisabetta Buscarini, Luigi Buscarini

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.

Original language	English
Pages (from-to)	2267-2275
Number of pages	9
Journal	Digestive Diseases and Sciences
Volume	39
Issue number	10
DOIs	https://doi.org/10.1007/BF02090383
Publication status	Published - Oct 1994

Keywords

adenomatous hyperplasia
hepatocellular carcinoma
small hepatic lesions
ultrasonically guided fine-needle biopsy

ASJC Scopus subject areas

Gastroenterology

Access to Document

10.1007/BF02090383

Fingerprint Dive into the research topics of 'Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients'. Together they form a unique fingerprint.

Cite this

Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients. / Fornari, Fabio; Filice, Carlo; Rapaccini, Gian Ludovico; Caturelli, Eugenio; Cavanna, Luigi; Civardi, Giuseppe; Di Stasi, Michele; Buscarini, Elisabetta; Buscarini, Luigi.

In: Digestive Diseases and Sciences, Vol. 39, No. 10, 10.1994, p. 2267-2275.

Research output: Contribution to journal › Article › peer-review

@article{759e058d3ae1411d9786955dc841eb94,

title = "Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients",

abstract = "Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.",

keywords = "adenomatous hyperplasia, hepatocellular carcinoma, small hepatic lesions, ultrasonically guided fine-needle biopsy",

author = "Fabio Fornari and Carlo Filice and Rapaccini, {Gian Ludovico} and Eugenio Caturelli and Luigi Cavanna and Giuseppe Civardi and {Di Stasi}, Michele and Elisabetta Buscarini and Luigi Buscarini",

year = "1994",

month = oct,

doi = "10.1007/BF02090383",

language = "English",

volume = "39",

pages = "2267--2275",

journal = "Digestive Diseases and Sciences",

issn = "0163-2116",

publisher = "Springer New York",

number = "10",

}

TY - JOUR

T1 - Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients

AU - Fornari, Fabio

AU - Filice, Carlo

AU - Rapaccini, Gian Ludovico

AU - Caturelli, Eugenio

AU - Cavanna, Luigi

AU - Civardi, Giuseppe

AU - Di Stasi, Michele

AU - Buscarini, Elisabetta

AU - Buscarini, Luigi

PY - 1994/10

Y1 - 1994/10

N2 - Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.

AB - Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.

KW - adenomatous hyperplasia

KW - hepatocellular carcinoma

KW - small hepatic lesions

KW - ultrasonically guided fine-needle biopsy

UR - http://www.scopus.com/inward/record.url?scp=0028170796&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028170796&partnerID=8YFLogxK

U2 - 10.1007/BF02090383

DO - 10.1007/BF02090383

M3 - Article

C2 - 7924754

AN - SCOPUS:0028170796

VL - 39

SP - 2267

EP - 2275

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

SN - 0163-2116

IS - 10

ER -

Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this