Abstract
Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.
| Original language | English |
|---|---|
| Pages (from-to) | 2267-2275 |
| Number of pages | 9 |
| Journal | Digestive Diseases and Sciences |
| Volume | 39 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 1994 |
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Keywords
- adenomatous hyperplasia
- hepatocellular carcinoma
- small hepatic lesions
- ultrasonically guided fine-needle biopsy
ASJC Scopus subject areas
- Gastroenterology
Cite this
Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients. / Fornari, Fabio; Filice, Carlo; Rapaccini, Gian Ludovico; Caturelli, Eugenio; Cavanna, Luigi; Civardi, Giuseppe; Di Stasi, Michele; Buscarini, Elisabetta; Buscarini, Luigi.
In: Digestive Diseases and Sciences, Vol. 39, No. 10, 10.1994, p. 2267-2275.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Small (≤3 cm) hepatic lesions - Results of sonographically guided fine-needld biopsy in 385 patients
AU - Fornari, Fabio
AU - Filice, Carlo
AU - Rapaccini, Gian Ludovico
AU - Caturelli, Eugenio
AU - Cavanna, Luigi
AU - Civardi, Giuseppe
AU - Di Stasi, Michele
AU - Buscarini, Elisabetta
AU - Buscarini, Luigi
PY - 1994/10
Y1 - 1994/10
N2 - Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.
AB - Three hundred ninety-five consecutive patients with sonographically detected hepatic lesions≤3 cm in diameter were submitted to ultrasonically guided fine-needle biopsy: 24 (6.1%) were≤1 cm in diameter; 142 (36%) were between 1.1 and 2 cm, and 229 (57.9%) were between 2.1 and 3 cm in diameter. In the 385 controlled cases, we obtained a cytohistological diagnosis of malignancy in 243 (63.1%): 135 hepatocellular carcinomas, 97 metastases, and 11 hepatic lymphomas. There were 104 true negatives (27%) and 38 false negatives (9.9%). The sensitivity of ultrasonically guided fine needle biopsy in the total series was 86.5%, the specificity 100%, with an overall accuracy of 90.1%. The overall accuracy was higher for lesions between 2.1 and 3 cm in diameter (90%) and was lower for lesions located in the sixth segment (84.6%). The correct diagnosis was obtained in the 83.3% (135/162) of small hepatocellular carcinomas versus 89.8% (97/108) in cases of small metastatic lesions.
KW - adenomatous hyperplasia
KW - hepatocellular carcinoma
KW - small hepatic lesions
KW - ultrasonically guided fine-needle biopsy
UR - http://www.scopus.com/inward/record.url?scp=0028170796&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028170796&partnerID=8YFLogxK
U2 - 10.1007/BF02090383
DO - 10.1007/BF02090383
M3 - Article
C2 - 7924754
AN - SCOPUS:0028170796
VL - 39
SP - 2267
EP - 2275
JO - Digestive Diseases and Sciences
JF - Digestive Diseases and Sciences
SN - 0163-2116
IS - 10
ER -