Small bowel capsule endoscopy revealing neuromuscular and vascular hamartoma of the jejunum: A case report

Maria L Caruso, Elisabetta Cavalcanti, Francesco De Michele, Antonia Ignazzi, Roberta Carullo, Mauro Mastronardi

Research output: Contribution to journalArticlepeer-review


RATIONALE: Digestive hemorrhage is a life-threatening and represents for both clinicians and patient a challenger problematic condition with the urgencies to discover the origin for correct the cause and safe the life of patient.

PATIENT CONCERNS: We report the case of a 58 -year-old man with extremely rare hamartomatous neurovascular lesion. Following recurrent episode of intestinal hemorrhage the patient underwent small bowel capsule endoscopy.

DIAGNOSES: Diagnosed with small intestine neoplasia.

INTERVENTIONS: The patient underwent curative small bowel resection. Histologic diagnosis was neuromuscular and vascular hamartoma (NMVH). In the small intestine, neoplastic lesions are very rare (2%) and mostly malformative while the more frequent cause of cryptic digestive hemorrhage remains angiodysplasia (50%) . The preexisting NMVH was exacerbated by the use of non-steroidal anti-inflammatory drugs, causing hemorrhage due to diffuse ulceration.

OUTCOMES: The patient stay healthy after treatment.

LESSONS: This is an hemorrhagic lesion with macroscopic "neoplastic" patterns due to abnormal mixing of normal indigenous tissue components. It poses a diagnostic challenge for clinicians and pathologists, but diagnosis is facilitated by capsule endoscopy and surgical treatment should provide definitive resolution.

Original languageEnglish
Pages (from-to)e0196
Issue number15
Publication statusPublished - Apr 2018


  • Capsule Endoscopy/methods
  • Diagnosis, Differential
  • Digestive System Surgical Procedures/methods
  • Dissection/methods
  • Gastrointestinal Hemorrhage/diagnosis
  • Hamartoma/complications
  • Humans
  • Intestinal Neoplasms/complications
  • Jejunum/blood supply
  • Male
  • Middle Aged
  • Recurrence
  • Treatment Outcome


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