Sindrome dell'intestino infetto: complicanza frequente dopo chirurgia addominale nel neonato.

Translated title of the contribution: Small bowel overgrowth: a frequent complication after abdominal surgery in newborns

L. Maestri, G. Fava, M. Fontana, E. Leva, G. Lista, S. Paccagnini, A. Pansini, G. Selvaggio, M. Torricelli, G. Zuin, L. Pansini, A. Bianchi

Research output: Contribution to journalArticle

Abstract

BACKGROUND/PURPOSE: Surgery for congenital or acquired gastroenterological disorders, and particularly that associated with short bowel, is not infrequently complicated by Small Bowel Bacterial Over growth (SBBO). Aim of this study is to evaluate the clinical course of children undergoing bowel surgery in the newborn period, assessing the development of SBBO and the response to intensive treatment with a "bowel cocktail" of gentamycin, metronidazole and cholestyramine. METHODS: 17 children with various conditions were studied clinically and by Breath Hydrogen Test (fasting and after glucose). 14 children underwent more than one procedure. All children were treated with overall "bowel cocktail" of gentamycin, metronidazole and cholestyramine. RESULTS: 5 children recovered after one course of treatment and 11 children relapsed at least once and required further courses of therapy. One child died from TPN related liver failure and another following a liver and small bowel transplant for short bowel syndrome. A third child required total intestinal tube splinting according to Sauer and another one required a tapering of the preatretic enlarged jejunal loop. CONCLUSIONS: Our study suggests that children undergoing bowel surgery in the neonatal period and those having more than one procedure are at greater risk of developing small bowel bacterial overgrowth postoperatively. Interestingly, loss of the ileocecal valve was not associated with an increased risk of bacterial overgrowth.

Translated title of the contributionSmall bowel overgrowth: a frequent complication after abdominal surgery in newborns
Original languageItalian
Pages (from-to)374-376
Number of pages3
JournalPediatria Medica e Chirurgica
Volume24
Issue number5
Publication statusPublished - Sep 2002

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Maestri, L., Fava, G., Fontana, M., Leva, E., Lista, G., Paccagnini, S., Pansini, A., Selvaggio, G., Torricelli, M., Zuin, G., Pansini, L., & Bianchi, A. (2002). Sindrome dell'intestino infetto: complicanza frequente dopo chirurgia addominale nel neonato. Pediatria Medica e Chirurgica, 24(5), 374-376.