Small hepatocellular carcinoma treated with percutaneous ethanol injection: MR imaging findings

S. Sironi, T. Livraghi, A. DelMaschio

Research output: Contribution to journalArticlepeer-review

Abstract

Fifty-seven magnetic resonance (MR) imaging examinations were obtained at 0.5 T in 19 patients before and after percutaneous ethanol injection (PEI) for 23 hepatocellular carcinoma (HCC) lesions less than 3.5 cm in diameter. Seventeen patients also underwent MR imaging 6 months after completion of therapy. In 11 patients, computed tomography was performed before and after treatment. After PEI, fine-needle biopsy specimens were obtained in all cases. Before treatment, HCC lesions had low signal intensity on T1-weighted images in 13 cases, had the same signal intensity as normal liver parenchyma in six, and had high signal intensity in four; all 23 tumors had high signal intensity on T2-weighted images. After treatment and at 6-month follow-up, all 21 lesions that contained no malignant cells at fine-needle biopsy had high signal intensity on T1-weighted images and had low signal intensity on T2-weighted images. The remaining two HCC lesions in which tumor necrosis was not achieved with PEI displayed a different MR pattern, since the residual neoplastic tissue showed no change in signal intensity on either T1- or T2-weighted images. The authors conclude that MR imaging may be useful for evaluating the effectiveness of PEI in achieving tumor regression.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalRadiology
Volume180
Issue number2
Publication statusPublished - 1991

Keywords

  • Alcohol, 761.1299
  • Liver neoplasms, MR studies, 761.1214
  • Liver neoplasms, therapy
  • Liver, interventional procedure, 761.1299

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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