Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism

D. S. Novikova, A. V. Garabadzhiu, G. Melino, N. A. Barlev, V. G. Tribulovich

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

Activated protein kinase (AMPK) is a key regulator of energy balance at both the cellular and wholebody levels. The activation of AMPK has a considerable potential in the therapy of a number of metabolic disorders as well as cancer. The achievements in the develop ment of smallmolecule activators of AMPK are reviewed.

Original languageEnglish
Pages (from-to)1497-1517
Number of pages21
JournalRussian Chemical Bulletin
Volume64
Issue number7
Publication statusPublished - Jul 1 2015

Fingerprint

AMP-Activated Protein Kinases
Modulators
Molecules
Energy balance
Protein Kinases
Chemical activation
Energy Metabolism

Keywords

  • AMPK activators
  • AMP—activated protein kinase
  • Drug design
  • Energy metabolism

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Novikova, D. S., Garabadzhiu, A. V., Melino, G., Barlev, N. A., & Tribulovich, V. G. (2015). Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism. Russian Chemical Bulletin, 64(7), 1497-1517.

Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism. / Novikova, D. S.; Garabadzhiu, A. V.; Melino, G.; Barlev, N. A.; Tribulovich, V. G.

In: Russian Chemical Bulletin, Vol. 64, No. 7, 01.07.2015, p. 1497-1517.

Research output: Contribution to journal › Article

Novikova, DS, Garabadzhiu, AV, Melino, G, Barlev, NA & Tribulovich, VG 2015, 'Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism', Russian Chemical Bulletin, vol. 64, no. 7, pp. 1497-1517.
Novikova DS, Garabadzhiu AV, Melino G, Barlev NA, Tribulovich VG. Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism. Russian Chemical Bulletin. 2015 Jul 1;64(7):1497-1517.
Novikova, D. S. ; Garabadzhiu, A. V. ; Melino, G. ; Barlev, N. A. ; Tribulovich, V. G. / Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism. In: Russian Chemical Bulletin. 2015 ; Vol. 64, No. 7. pp. 1497-1517.
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