Abstract
Activated protein kinase (AMPK) is a key regulator of energy balance at both the cellular and wholebody levels. The activation of AMPK has a considerable potential in the therapy of a number of metabolic disorders as well as cancer. The achievements in the develop ment of smallmolecule activators of AMPK are reviewed.
| Original language | English |
|---|---|
| Pages (from-to) | 1497-1517 |
| Number of pages | 21 |
| Journal | Russian Chemical Bulletin |
| Volume | 64 |
| Issue number | 7 |
| Publication status | Published - Jul 1 2015 |
Keywords
- AMPK activators
- AMP—activated protein kinase
- Drug design
- Energy metabolism
ASJC Scopus subject areas
- Chemistry(all)
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Novikova, D. S., Garabadzhiu, A. V., Melino, G., Barlev, N. A., & Tribulovich, V. G. (2015). Small-molecule activators of AMP-activated protein kinase as modulators of energy metabolism. Russian Chemical Bulletin, 64(7), 1497-1517.