Abstract
Activated protein kinase (AMPK) is a key regulator of energy balance at both the cellular and wholebody levels. The activation of AMPK has a considerable potential in the therapy of a number of metabolic disorders as well as cancer. The achievements in the develop ment of smallmolecule activators of AMPK are reviewed.
Original language | English |
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Pages (from-to) | 1497-1517 |
Number of pages | 21 |
Journal | Russian Chemical Bulletin |
Volume | 64 |
Issue number | 7 |
Publication status | Published - Jul 1 2015 |
Keywords
- AMPK activators
- AMP—activated protein kinase
- Drug design
- Energy metabolism
ASJC Scopus subject areas
- Chemistry(all)