Small nodular melanoma: The beginning of a life-threatening lesion. A clinical study on 11 cases

Aldo Bono, Elena Tolomio, Antonino Carbone, Daniele Moglia, Federica Crippa, Stefano Tomatis, Mario Santinami

Research output: Contribution to journalArticle

Abstract

Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalTumori
Volume97
Issue number1
DOIs
Publication statusPublished - Jan 2011

Fingerprint

Beginning of Human Life
Early Diagnosis
Melanoma
Secondary Prevention
Physicians
Recurrence
Skin
Clinical Studies

Keywords

  • Diagnosis
  • Nodular melanoma
  • Prognosis
  • Small melanoma

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Small nodular melanoma : The beginning of a life-threatening lesion. A clinical study on 11 cases. / Bono, Aldo; Tolomio, Elena; Carbone, Antonino; Moglia, Daniele; Crippa, Federica; Tomatis, Stefano; Santinami, Mario.

In: Tumori, Vol. 97, No. 1, 01.2011, p. 35-38.

Research output: Contribution to journalArticle

@article{201601e69c6f43c086072db1a558db17,
title = "Small nodular melanoma: The beginning of a life-threatening lesion. A clinical study on 11 cases",
abstract = "Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.",
keywords = "Diagnosis, Nodular melanoma, Prognosis, Small melanoma",
author = "Aldo Bono and Elena Tolomio and Antonino Carbone and Daniele Moglia and Federica Crippa and Stefano Tomatis and Mario Santinami",
year = "2011",
month = "1",
doi = "10.1700/611.7158",
language = "English",
volume = "97",
pages = "35--38",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "1",

}

TY - JOUR

T1 - Small nodular melanoma

T2 - The beginning of a life-threatening lesion. A clinical study on 11 cases

AU - Bono, Aldo

AU - Tolomio, Elena

AU - Carbone, Antonino

AU - Moglia, Daniele

AU - Crippa, Federica

AU - Tomatis, Stefano

AU - Santinami, Mario

PY - 2011/1

Y1 - 2011/1

N2 - Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.

AB - Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.

KW - Diagnosis

KW - Nodular melanoma

KW - Prognosis

KW - Small melanoma

UR - http://www.scopus.com/inward/record.url?scp=79953838442&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79953838442&partnerID=8YFLogxK

U2 - 10.1700/611.7158

DO - 10.1700/611.7158

M3 - Article

C2 - 21528661

AN - SCOPUS:79953838442

VL - 97

SP - 35

EP - 38

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 1

ER -