Abstract
Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.
| Original language | English |
|---|---|
| Pages (from-to) | 35-38 |
| Number of pages | 4 |
| Journal | Tumori |
| Volume | 97 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2011 |
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Keywords
- Diagnosis
- Nodular melanoma
- Prognosis
- Small melanoma
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Small nodular melanoma : The beginning of a life-threatening lesion. A clinical study on 11 cases. / Bono, Aldo; Tolomio, Elena; Carbone, Antonino; Moglia, Daniele; Crippa, Federica; Tomatis, Stefano; Santinami, Mario.
In: Tumori, Vol. 97, No. 1, 01.2011, p. 35-38.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Small nodular melanoma
T2 - The beginning of a life-threatening lesion. A clinical study on 11 cases
AU - Bono, Aldo
AU - Tolomio, Elena
AU - Carbone, Antonino
AU - Moglia, Daniele
AU - Crippa, Federica
AU - Tomatis, Stefano
AU - Santinami, Mario
PY - 2011/1
Y1 - 2011/1
N2 - Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.
AB - Aims and background. Because of its high thickness, nodularmelanoma often bears a poor prognosis. Thus, an earlier diagnosis of this type of lesion while it is still thin would be an important step in secondary prevention. The principal aimof the present study was to better define the initial clinical features of nodular melanoma to allow an early diagnosis. A secondary aim was to establish the prognosis of this type of lesion. Methods. We retrospectively studied and illustrated the clinical features of 11 small (≤6mm maximum diameter) cutaneous nodularmelanomas seen and treated during a 10-year period. Prognostic characteristics of the various lesions were also described. Results. The results of the study help to describe a small nodularmelanoma as a dark and/or pink/red raised lesion, which may be evenly or unevenly colored, with well-defined borders, that often appears de novo. A correct clinical diagnosis was made in 7 of the cases. During amedian follow-up of 6 years, none of the patients had local or distant relapses. Conclusions. Detection of small nodular melanoma is feasible by accurate visual inspection, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level to bring about curative surgery. Free full text available at www.tumorionline.it.
KW - Diagnosis
KW - Nodular melanoma
KW - Prognosis
KW - Small melanoma
UR - http://www.scopus.com/inward/record.url?scp=79953838442&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953838442&partnerID=8YFLogxK
U2 - 10.1700/611.7158
DO - 10.1700/611.7158
M3 - Article
C2 - 21528661
AN - SCOPUS:79953838442
VL - 97
SP - 35
EP - 38
JO - Tumori
JF - Tumori
SN - 0300-8916
IS - 1
ER -